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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: miR-100 inhibits cell proliferation in mantle cell lymphoma by targeting mTOR

Fig. 3

LV-miR-100 upregulated miR-100 and down regulated mTOR mRNA and protein levels. a RT-PCR showed that the miR-100 mRNA level was increased in the LV-miR-100-up group compared to the NC group in Jeko-1 cells (p = 0.0003). b RT-PCR showed that the miR-100 mRNA level was increased in the LV-miR-100-up group compared to the NC group in Mino cells (p = 0.0013). c RT-PCR showed that the mTOR mRNA level was decreased in the LV-miR-100-up group compared to the NC group in Jeko-1 cells (p = 0.0005). d RT-PCR showed that the mTOR mRNA level was decreased in the LV-miR-100-up group compared to the NC group in Mino cells (p = 0.0003). e Western blot detected the mTOR protein of Jeko-1 cell lines. f The expression of mTOR protein in the LV-miR-100-up and LV-mTOR-RNAi groups was decreased compared to the control group and NC group in Jeko-1 cells. g Western blot detected the mTOR protein of Mino cell lines. h The expression of mTOR protein in the LV-miR-100-up and LV-mTOR-RNAi groups was decreased compared to the control group and NC group in Mino cells

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