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Fig. 4 | Experimental Hematology & Oncology

Fig. 4

From: Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways

Fig. 4

Regulatory pathways of PD-L1 via deubiquitination. The deubiquitination of PD-L1 involves a family of ubiquitin-specific proteases (USPs), namely, USP2, USP5, USP7, USP8, USP9X, USP20, USP22, USP28, and USP51, along with CSN5, UCHL1, OTUB1, and microRNAs (miR-199a-5p and miR-328-3p). Positive regulatory interactions are denoted by black arrows

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Experimental Hematology & Oncology

ISSN: 2162-3619

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