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Table 1 Clinical characteristics of MCL patients

From: A novel CAR-T cell product targeting CD74 is an effective therapeutic approach in preclinical mantle cell lymphoma models

Patient ID

Diagnosis

Treatment

Immunophenotype

1 (DA)

MCL

Treatment naive

CD5+CD19+ (86.1%+)

2 (U-21-0319)

MCL

Treatment naive

CD5+CD19+ (85.5%+)

3 (U-21-2484)

MCL

R/R status post chemotherapy including ASCT, targeted therapies including ibrutinib and venetoclax, and progressed after commercial CD19 CAR-Ts

CD5+CD19+ (95.2%+)

4 (U-18-0530)

MCL

Treatment naive

CD5+CD19+ (85.4%+)

5 (U-19-1409)

MCL

R/R status post chemotherapy and ibrutinib

CD5−CD19+ (73.7%+)