Fig. 2

Antibody–drug conjugates used in R/R DLBCLs. This picture shows the mechanisms and processes of antibody–drug conjugates in lymphoma patients. Once the antibody binds the target antigen on the tumor cell surface. The complex is rapidly endocytosed and transported to lysosomes, where the effector molecule MMAE is released into the cytoplasm leading to cell toxicity. ADC antibody–drug conjugate