Fig. 2
From: Chimeric antigen receptor engineered natural killer cells for cancer therapy
The research progress, advantages, and limitations of various NK cell sources. NK cells can be obtained from 5 different sources: PB, UCB, iPSC, hESC, and NK cell lines. Most cell sources have remarkable tumor-eliminating ability and provide clinically meaningful benefit, having transitioned into in-human studies of different stages. Each source of NK cells has its own set of strengths and limitations