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Fig. 4 | Experimental Hematology & Oncology

Fig. 4

From: Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing

Fig. 4

A significant increase in TIGIT+ NK cells at relapse after BCMA CAR-T cell therapy in R/R-MM. A The tSNE plots of NK cells at baseline and progression. B The heatmap of differentially expressed genes in each cluster. C The proportions of NK cells of all the clusters at baseline and progression. D Dot plot of TIGIT and CD69 expression in each cluster. E The violin diagram of TIGIT expression in each cluster

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