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Fig. 1 | Experimental Hematology & Oncology

Fig. 1

From: Single-cell transcriptome analysis reveals stem cell-like subsets in the progression of Waldenström’s macroglobulinemia

Fig. 1

Atlas and Transcriptomic profiling in patients with WM and IgM MGUS. A UMAP plot of merged single-cell transcriptomes. Cells are colored according to cell type. B Cell proportion of each sub-cluster in three groups. C Expression of DEGs of mature B cells and immunoglobin genes in patients or healthy donors. D Heatmap showing CNV levels of clusters originated from different samples. Red represents high CNV level and blue represents low CNV level. Horizontal axis represents distribution of genomic regions. E SCENIC analysis estimates transcription factors regulating indicated clusters. F Scatter plots showing significantly DEGs of plasma cells across the three groups

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