Fig. 9

Effects of GPR109A and NETs on the number of bacteria in liver, spleen, lung, kidney and blood. We constructed CLP models in WT + CLP, WT + DNase I + CLP and GPR109A^−/− + CLP groups respectively, and collected the liver, spleen, lung, kidney and blood of mice after 3 days. Then the bacteria of blood, liver, spleen, lung and kidney were counted. a–e The number of bacteria in blood, liver, spleen, lung and kidney. Values are presented as means ± SEM (n = 10) (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001)