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Fig. 7 | Experimental Hematology & Oncology

Fig. 7

From: GPR109A controls neutrophil extracellular traps formation and improve early sepsis by regulating ROS/PAD4/Cit-H3 signal axis

Fig. 7

MPO levels of liver, spleen, lung and kidney. We constructed CLP models in WT + CLP, WT + DNaseI + CLP and GPR109A−/− + CLP groups respectively, and collected the liver, spleen, lung and kidney of mice after 3 days. NT means no treatment, Shame means Only surgery was performed without puncture or ligation of the cecum, CLP means cecal puncture and ligation were performed, DNaseI + CLP means Cecal puncture and ligation were performed and DNaseI was injected. a–d MPO levels of liver, spleen, lung and kidney. Values are presented as means ± SEM (n = 10) (∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001)

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