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Fig. 8 | Experimental Hematology & Oncology

Fig. 8

From: CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway

Fig. 8

NF-YA/CDCA8 axis promotes HCC growth and metastasis. a CDCA8 and NF-YA levels were evaluated in HCC cell lines transfected with the three siRNA for NF-YA. b CCK-8 and c The colony survival assay were performed. d Measurement of cell migration by transwell assay using cell describe in a. e, f Measurement of cell migration by transwell assays using HepG2 and Huh7 cells with NF-YA or vector, and inhibition of CDCA8 in NF-YA overexpressing cells. g The relative enrichment of NF-YA and lgG in Huh7 and HepG2 cells. (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001)

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