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Fig. 6 | Experimental Hematology & Oncology

Fig. 6

From: CDCA8 induced by NF-YA promotes hepatocellular carcinoma progression by regulating the MEK/ERK pathway

Fig. 6

CDCA8 mediates the expression of TPM3, NECAP2, and USP13 in HCC cells. a The volcano map. b Veen diagram c The heatmap d Kaplan–Meier analysis was used to assess the effect of TPM3, NECAP2, USP13, and SPRYD4 on HCC patient survival. e The scatter plot were used to describe the relationship between CDCA8 and TPM3, NECAP2, USP13, SPRYD4 in HCC samples. f qRT-PCR were performed in four cell lines with CDCA8 inhibition. g, h Representative pictures of (g) migration and (h) invasion assays with or without PD98059 or SCH77298 or siRNA targeting TPM3, NECAP2, and USP13 in PLC/PRF/5 cells. (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001)

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Experimental Hematology & Oncology

ISSN: 2162-3619

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