Table 2 Potential driver mutations in pGI-DLBCL
#Gene Symbol | Sample | COSMIC | MDG125 | SMG127 | CDG291 | Patient_Number_Count |
|---|---|---|---|---|---|---|
TP53 | P01, P02, P03, P04, P05, P17, P18, P19, P20, P21, P22, P23, P33, P34, P35, P36, P37, P41, P42, P43, P50, P51 | oncogene, TSG, fusion | TSG | pancan_fre:42.00% | Yes | 22 |
P2RY8 | P09, P12, P13, P17, P18, P19, P20, P25, P27, P29, P30, P38, P52, P53 | oncogene, fusion | No | No | No | 14 |
KMT2D | P02, P08, P10, P21, P31, P32, P34, P40, P43, P46, P53 | oncogene, TSG | No | No | No | 11 |
MUC16 | P01, P03, P09, P10, P13, P24, P36, P45, P50, P51 | oncogene | No | No | No | 10 |
CSMD3 | P03, P06, P09, P21, P24, P28, P38, P45, P50, P53 | TSG | No | No | No | 10 |
FAT4 | P01, P06, P08, P09, P19, P20, P27, P50, P52 | TSG | No | No | No | 9 |
CCND3 | P06, P07, P11, P18, P22, P28, P40, P45, P48 | oncogene, fusion | No | No | No | 9 |
HIST1H1C | P06, P14, P18, P26, P27, P34, P38, P53 | No | No | pancan_fre:0.60% | Yes | 8 |
CARD11 | P01, P20, P40, P43, P45, P46, P48, P52 | oncogene | Oncogene | No | No | 8 |
MYC | P04, P14, P22, P26, P33, P34, P37, P50 | oncogene, fusion | No | No | No | 8 |
LRP1B | P04, P19, P20, P26, P36, P38, P41, P52 | TSG | No | No | No | 8 |
B2M | P06, P09, P11, P20, P27, P31, P38 | TSG | TSG | No | Yes | 7 |
TET2 | P07, P11, P14, P16, P27, P28, P50 | TSG | TSG | pancan_fre:1.60% | Yes | 7 |
FOXO1 | P04, P11, P14, P15, P29, P34, P50 | oncogene, TSG, fusion | No | No | No | 7 |
EBF1 | P01, P04, P17, P18, P26, P32, P53 | TSG, fusion | No | No | No | 7 |
BTG1 | P06, P25, P27, P38, P39, P40, P42 | TSG, fusion | No | No | No | 7 |
SETD1B | P08, P18, P31, P33, P46, P47, P52 | TSG | No | No | No | 7 |
BCR | P15, P18, P26, P35, P48, P53 | fusion | No | No | No | 6 |
COL3A1 | P05, P10, P23, P24, P28, P38 | fusion | No | No | No | 6 |
DDX3X | P09, P10, P20, P29, P32, P50 | TSG | No | No | Yes | 6 |
AHNAK2 | P04, P06, P20, P24, P26, P31 | No | No | No | Yes | 6 |
PIM1 | P21, P26, P35, P37, P46, P52 | oncogene, fusion | No | No | No | 6 |
ID3 | P14, P15, P22, P26, P29, P51 | TSG | No | No | No | 6 |
DNM2 | P01, P13, P20, P28, P38, P40 | TSG | No | No | No | 6 |
PTPN6 | P06, P11, P12, P25, P38 | TSG | No | No | No | 5 |
FAT1 | P03, P07, P09, P13, P36 | TSG | No | No | No | 5 |
ROBO2 | P03, P06, P19, P24, P33 | TSG | No | No | No | 5 |
NFKBIA | P12, P18, P43, P50, P53 | No | No | No | No | 5 |
BCL7A | P12, P26, P34, P40, P53 | fusion | No | No | No | 5 |
SGK1 | P04, P06, P18, P25, P28 | oncogene | No | No | Yes | 5 |
ZEB2 | P06, P13, P31, P48 | No | No | No | Yes | 4 |
MEF2B | P08, P34, P47, P52 | No | No | No | No | 4 |
PRDM1 | P36, P37, P44, P45 | TSG | TSG | No | No | 4 |
CD79B | P02, P03, P08, P46 | oncogene | No | No | No | 4 |
NFKBIE | P17, P19, P38, P48 | TSG | No | No | No | 4 |
SOCS1 | P26, P28, P38, P43 | TSG | TSG | No | No | 4 |
FAT3 | P05, P20, P21, P40 | Â | No | No | No | 4 |
CHD4 | P07, P24, P35, P40 | oncogene | No | No | Yes | 4 |
NCOR2 | P02, P20, P36, P42 | TSG | No | No | Yes | 4 |
ZFP36L2 | P08, P20, P26, P39 | No | No | No | Yes | 4 |
DST | P04, P05, P45, P47 | No | No | No | Yes | 4 |
KIAA1549 | P20, P37, P40, P43 | fusion | No | No | No | 4 |
AHNAK | P17, P45, P47, P51 | No | No | No | Yes | 4 |
GNAQ | P06, P38, P46, P51 | oncogene | Oncogene | No | No | 4 |
TBL1XR1 | P06, P18, P26, P51 | oncogene, TSG, fusion | No | pancan_fre:0.80% | Yes | 4 |
HLA-B | P13, P19, P24, P27 | No | No | No | Yes | 4 |
BRAF | P01, P04, P06, P53 | oncogene, fusion | Oncogene | pancan_fre:1.50% | Yes | 4 |
ACTB | P06, P17, P20, P35 | No | No | No | Yes | 4 |
PLEC | P06, P11, P28, P40 | No | No | No | Yes | 4 |
SYNE1 | P04, P06, P33, P34 | No | No | No | Yes | 4 |
DCC | P03, P24, P36, P52 | Â | No | No | No | 4 |
ROS1 | P01, P20, P24, P45 | oncogene, fusion | No | No | No | 4 |
ARID1A | P04, P11, P18, P22 | TSG, fusion | TSG | pancan_fre:5.40% | Yes | 4 |
TNFRSF14 | P06, P11, P14, P25 | TSG | No | No | No | 4 |
STAT3 | P04, P18, P19, P48 | oncogene | No | No | Yes | 4 |
PIK3CD | P13, P16, P20 | No | No | No | No | 3 |
FAM135B | P06, P20, P38 | Â | No | No | No | 3 |
TRIO | P04, P36, P40 | No | No | No | Yes | 3 |
TRIM24 | P03, P20, P50 | oncogene, TSG, fusion | No | No | No | 3 |
UBR5 | P04, P20, P43 | TSG | No | No | No | 3 |
FAM47C | P04, P17, P34 | Â | No | No | No | 3 |
LRRK2 | P09, P42, P52 | No | No | pancan_fre:2.80% | Yes | 3 |
GRIN2A | P01, P04, P20 | TSG | No | No | No | 3 |
FBN2 | P01, P09, P20 | No | No | No | Yes | 3 |
NEB | P01, P36, P51 | No | No | No | Yes | 3 |
IRS2 | P02, P50, P53 | No | No | No | Yes | 3 |
PRKCD | P06, P11, P24 | No | No | No | Yes | 3 |
ACTG1 | P06, P14, P26 | No | No | No | Yes | 3 |
KALRN | P20, P31, P43 | No | No | No | Yes | 3 |
BIRC6 | P06, P09, P20 | oncogene, fusion | No | No | No | 3 |
CLTC | P16, P20, P50 | TSG, fusion | No | No | Yes | 3 |
APC | P06, P18, P36 | TSG | TSG | pancan_fre:7.30% | Yes | 3 |
PTEN | P01, P09, P35 | TSG | TSG | pancan_fre:9.70% | Yes | 3 |
CXCR4 | P01, P26, P50 | oncogene | No | No | No | 3 |
JMJD1C | P03, P08, P12 | No | No | No | Yes | 3 |
FAS | P06, P09, P18 | TSG | No | No | No | 3 |
BCL6 | P05, P43, P52 | oncogene, fusion | No | No | No | 3 |
PCBP1 | P09, P44, P46 | Â | No | pancan_fre:0.30% | Yes | 3 |
BCL11B | P07, P11, P12 | oncogene, TSG, fusion | No | No | No | 3 |
PTPRB | P01, P36, P50 | TSG | No | No | No | 3 |
CIITA | P11, P25, P40 | TSG, fusion | No | No | No | 3 |
HGF | P09, P36, P48 | No | No | pancan_fre:1.70% | Yes | 3 |
IRF4 | P08, P38, P42 | oncogene, TSG, fusion | No | No | No | 3 |
NIN | P17, P27, P36 | fusion | No | No | Yes | 3 |
RARA | P10, P33, P48 | oncogene, fusion | No | No | No | 3 |
TRRAP | P20, P36, P50 | oncogene | No | No | No | 3 |
MAP2K1 | P12, P28, P50 | oncogene | Oncogene | No | No | 3 |
KMT2C | P05, P11, P15 | TSG | No | No | No | 3 |
PABPC1 | P25, P26, P32 | oncogene, TSG | No | No | Yes | 3 |
PIK3CB | P32, P53 | oncogene | No | No | Yes | 2 |
CBLB | P26, P52 | TSG | No | No | No | 2 |
MDN1 | P09, P53 | No | No | No | Yes | 2 |
RAB11FIP5 | P07, P20 | No | No | No | Yes | 2 |
FIP1L1 | P01, P15 | fusion | No | No | No | 2 |
CFH | P09, P20 | No | No | No | Yes | 2 |
KDM6B | P26, P53 | No | No | No | Yes | 2 |
MYCN | P25, P27 | oncogene | No | No | No | 2 |
CAMTA1 | P37, P51 | TSG, fusion | No | No | No | 2 |
TCF7 | P41, P44 | No | No | No | Yes | 2 |
PDGFRA | P20, P40 | oncogene, fusion | Oncogene | pancan_fre:1.90% | Yes | 2 |
TET1 | P09, P20 | oncogene, TSG, fusion | No | No | No | 2 |
ARHGAP32 | P01, P04 | No | No | No | Yes | 2 |
SFRP4 | P09, P12 | TSG | No | No | No | 2 |
PRRC2A | P20, P50 | No | No | No | Yes | 2 |
NTRK2 | P04, P25 | No | No | No | No | 2 |
HSP90AB1 | P11, P20 | fusion | No | No | Yes | 2 |
KRAS | P25, P28 | oncogene | Oncogene | pancan_fre:6.70% | Yes | 2 |
PCM1 | P06, P24 | fusion | No | No | Yes | 2 |
SMARCA4 | P15, P28 | TSG | TSG | No | Yes | 2 |
CHD8 | P38, P50 | No | No | No | Yes | 2 |
NCOR1 | P03, P32 | TSG | TSG | pancan_fre:2.20% | Yes | 2 |
ZFP36L1 | P26, P46 | No | No | No | Yes | 2 |
MKI67 | P17, P45 | No | No | No | Yes | 2 |
RGPD3 | P45, P48 | Â | No | No | No | 2 |
FBXO11 | P07, P51 | TSG | No | No | Yes | 2 |
LRIG3 | P01, P20 | TSG, fusion | No | No | No | 2 |
NFATC2 | P08, P43 | oncogene, fusion | No | No | No | 2 |
KIT | P10, P23 | oncogene | Oncogene | pancan_fre:1.40% | Yes | 2 |
CREBBP | P09, P20 | oncogene, TSG, fusion | TSG | No | No | 2 |
TCL1A | P07, P25 | oncogene, fusion | No | No | No | 2 |
MSH3 | P12, P42 | No | No | No | No | 2 |
SF3B1 | P01, P11 | oncogene | Oncogene | pancan_fre:1.30% | Yes | 2 |
PRKCB | P04, P13 | Â | No | No | No | 2 |
ZNF91 | P24, P40 | No | No | No | Yes | 2 |
BCLAF1 | P09, P53 | Â | No | No | Yes | 2 |
MAP3K4 | P11, P13 | No | No | No | Yes | 2 |
FGFR4 | P45, P50 | oncogene | No | No | No | 2 |
FGFR2 | P45, P52 | oncogene, fusion | Oncogene | pancan_fre:1.50% | Yes | 2 |
PRPF8 | P01, P09 | No | No | No | Yes | 2 |
SPEN | P11, P38 | TSG | No | No | Yes | 2 |
SPEG | P45, P53 | No | No | No | Yes | 2 |
PDE4DIP | P03, P38 | fusion | No | No | No | 2 |
AFF3 | P01, P17 | oncogene, fusion | No | No | No | 2 |
SALL4 | P40, P50 | oncogene | No | No | No | 2 |
ANKRD11 | P04, P35 | No | No | No | Yes | 2 |
TFDP1 | P26, P42 | No | No | No | Yes | 2 |
INPP4B | P36, P50 | No | No | No | No | 2 |
MICAL1 | P09, P40 | No | No | No | Yes | 2 |
SIN3A | P15, P34 | No | No | pancan_fre:1.10% | Yes | 2 |
HLA-A | P12, P18 | fusion | No | No | Yes | 2 |
TFEB | P04, P28 | oncogene, fusion | No | No | No | 2 |
KIAA1109 | P20, P40 | No | No | No | Yes | 2 |
TNFAIP3 | P11, P36 | TSG | TSG | No | No | 2 |
TP63 | P09, P11 | oncogene, TSG | No | No | No | 2 |
PTPRD | P40, P45 | TSG | No | No | No | 2 |
CLTCL1 | P20, P48 | TSG, fusion | No | No | Yes | 2 |
ZMYM3 | P09, P20 | TSG | No | No | No | 2 |
MGA | P01, P41 | No | No | No | Yes | 2 |
NSD1 | P48, P51 | fusion | No | pancan_fre:2.40% | Yes | 2 |
CSF1R | P20, P42 | oncogene | Oncogene | No | No | 2 |
MEGF6 | P11, P45 | No | No | No | Yes | 2 |
HIST1H3B | P01, P26 | oncogene | Oncogene | No | No | 2 |
ADCY1 | P03, P20 | No | No | No | Yes | 2 |
RET | P17, P27 | oncogene, fusion | Oncogene | No | No | 2 |
EPHA7 | P26, P36 | Â | No | No | No | 2 |
EPHA3 | P20, P51 | Â | No | pancan_fre:2.10% | Yes | 2 |
RBM15 | P04, P09 | fusion | No | No | No | 2 |
ZNF521 | P08, P09 | oncogene, fusion | No | No | No | 2 |
CNTNAP2 | P09, P35 | TSG | No | No | No | 2 |
RASA1 | P28, P51 | No | No | No | Yes | 2 |
PTPRC | P26, P31 | TSG | No | No | No | 2 |
CAD | P20, P37 | No | No | No | Yes | 2 |
EPS15 | P32, P50 | TSG, fusion | No | No | No | 2 |
EXT2 | P05, P20 | TSG | No | No | No | 2 |
RAG1 | P24, P38 | No | No | No | Yes | 2 |
CDH10 | P03, P12 | TSG | No | No | No | 2 |
ZFHX3 | P01, P20 | TSG | No | No | Yes | 2 |
MTOR | P07, P51 | oncogene | No | pancan_fre:3.00% | Yes | 2 |
EP300 | P06, P09 | TSG, fusion | TSG | pancan_fre:2.50% | Yes | 2 |
CNBD1 | P06, P12 | Â | No | No | No | 2 |
ABCB1 | P24, P42 | No | No | No | Yes | 2 |
CTNNA2 | P09, P25 | oncogene | No | No | No | 2 |
NOTCH1 | P33, P37 | oncogene, TSG, fusion | TSG | pancan_fre:3.10% | Yes | 2 |
IKBKB | P09, P27 | oncogene | No | No | No | 2 |
MYO5A | P01, P38 | fusion | No | No | No | 2 |
STRN | P20, P50 | fusion | No | No | No | 2 |
NRG1 | P20, P53 | TSG, fusion | No | No | No | 2 |
MALT1 | P28, P48 | oncogene, fusion | No | No | No | 2 |
PHF6 | P08, P20 | TSG | TSG | pancan_fre:0.80% | Yes | 2 |
NAV3 | P04, P45 | No | No | pancan_fre:4.60% | Yes | 2 |
MYCBP2 | P04, P43 | No | No | No | Yes | 2 |
NBEA | P48, P53 | Â | No | No | Yes | 2 |
HSP90AA1 | P04, P26 | fusion | No | No | No | 2 |
CHD7 | P31, P37 | No | No | No | Yes | 2 |
PIK3CG | P52 | No | No | pancan_fre:1.70% | Yes | 1 |
HIST1H4I | P14 | fusion | No | No | No | 1 |
HSPA8 | P04 | No | No | No | Yes | 1 |
NUP98 | P20 | oncogene, fusion | No | No | Yes | 1 |
XPA | P46 | TSG | No | No | No | 1 |
CEP89 | P04 | fusion | No | No | No | 1 |
XPO1 | P28 | oncogene | No | No | No | 1 |
CSDE1 | P51 | No | No | No | Yes | 1 |
TTK | P09 | No | No | No | Yes | 1 |
COL1A1 | P26 | fusion | No | No | No | 1 |
ZEB1 | P52 | oncogene | No | No | No | 1 |
ITGAV | P13 | Â | No | No | No | 1 |
ZNF703 | P14 | No | No | No | Yes | 1 |
ERBB2IP | P14 | No | No | No | Yes | 1 |
ARHGEF12 | P20 | TSG, fusion | No | No | No | 1 |
MUC1 | P29 | fusion | No | No | No | 1 |
EWSR1 | P20 | oncogene, fusion | No | No | Yes | 1 |
AHCTF1 | P26 | No | No | No | Yes | 1 |
RPL22 | P09 | TSG, fusion | No | pancan_fre:1.00% | Yes | 1 |
SIX2 | P22 | oncogene | No | No | No | 1 |
PRX | P20 | No | No | pancan_fre:0.90% | Yes | 1 |
ARID2 | P06 | TSG | TSG | No | Yes | 1 |
SET | P20 | oncogene, fusion | No | No | No | 1 |
ELK4 | P36 | oncogene, fusion | No | No | No | 1 |
TRIM7 | P46 | No | No | No | Yes | 1 |
FBXW7 | P05 | TSG | TSG | pancan_fre:3.00% | Yes | 1 |
TGFBR2 | P11 | TSG | No | pancan_fre:1.10% | Yes | 1 |
SH3PXD2A | P20 | No | No | No | Yes | 1 |
SVIL | P20 | No | No | No | Yes | 1 |
PHLDA1 | P21 | No | No | No | Yes | 1 |
NBPF10 | P28 | No | No | No | Yes | 1 |
PBX1 | P50 | oncogene, fusion | No | No | No | 1 |
ARHGAP35 | P20 | No | No | pancan_fre:2.50% | Yes | 1 |
PTCH1 | P33 | TSG | TSG | No | No | 1 |
CUL1 | P23 | No | No | No | Yes | 1 |
CDX2 | P20 | TSG, fusion | No | No | No | 1 |
PTPN13 | P12 | TSG | No | No | Yes | 1 |
IRS4 | P09 | oncogene, TSG | No | No | No | 1 |
DMD | P06 | No | No | No | Yes | 1 |
PPM1D | P09 | oncogene | No | No | No | 1 |
SRSF2 | P14 | oncogene | Oncogene | No | No | 1 |
RALGAPA1 | P17 | No | No | No | Yes | 1 |
EIF1AX | P04 | Â | No | No | No | 1 |
MED12 | P11 | TSG | Oncogene | No | Yes | 1 |
NTRK3 | P45 | oncogene, fusion | No | No | No | 1 |
MED13 | P20 | No | No | No | Yes | 1 |
ARHGAP26 | P21 | TSG, fusion | No | No | No | 1 |
SRGAP3 | P01 | fusion | No | No | No | 1 |
ACSL6 | P01 | fusion | No | No | No | 1 |
FLI1 | P01 | oncogene, fusion | No | No | No | 1 |
CHD2 | P28 | TSG | No | No | No | 1 |
POLG | P20 | TSG | No | No | No | 1 |
DDX5 | P23 | oncogene, fusion | No | No | Yes | 1 |
MN1 | P52 | oncogene, fusion | No | No | Yes | 1 |
PRDM16 | P24 | oncogene, fusion | No | No | No | 1 |
POT1 | P53 | TSG | No | No | No | 1 |
ARHGAP5 | P20 | oncogene | No | No | No | 1 |
SOS1 | P51 | No | No | No | Yes | 1 |
KIF20B | P20 | No | No | No | Yes | 1 |
TSHZ2 | P47 | No | No | pancan_fre:1.80% | No | 1 |
EIF3E | P45 | TSG, fusion | No | No | No | 1 |
BCL2L12 | P39 | oncogene | No | No | No | 1 |
KAT6A | P41 | oncogene, fusion | No | No | No | 1 |
CDH11 | P27 | TSG, fusion | No | No | No | 1 |
BAP1 | P53 | TSG | TSG | pancan_fre:2.00% | Yes | 1 |
UBE4A | P20 | No | No | No | Yes | 1 |
JAK2 | P09 | oncogene, fusion | Oncogene | No | Yes | 1 |
N4BP2 | P26 | TSG | No | No | No | 1 |
GRM3 | P13 | oncogene | No | No | No | 1 |
ZNF384 | P06 | fusion | No | No | No | 1 |
AKAP9 | P01 | fusion | No | No | Yes | 1 |
EEF1A1 | P08 | No | No | No | Yes | 1 |
PBRM1 | P20 | TSG | TSG | pancan_fre:5.40% | Yes | 1 |
ERC1 | P48 | fusion | No | No | No | 1 |
ERG | P36 | oncogene, fusion | No | No | No | 1 |
MYOD1 | P36 | oncogene | No | No | No | 1 |
CDK12 | P25 | TSG | No | pancan_fre:1.50% | Yes | 1 |
A1CF | P45 | oncogene | No | No | No | 1 |
WT1 | P23 | oncogene, TSG, fusion | TSG | pancan_fre:1.00% | Yes | 1 |
BARD1 | P31 | TSG | No | No | Yes | 1 |
BAZ1A | P31 | TSG | No | No | No | 1 |
FN1 | P01 | No | No | No | Yes | 1 |
FUBP1 | P51 | oncogene | TSG | No | No | 1 |
PRRX1 | P51 | fusion | No | No | No | 1 |
ATR | P25 | TSG | No | pancan_fre:2.40% | Yes | 1 |
BRIP1 | P53 | TSG | No | No | No | 1 |
FLT1 | P01 | No | No | No | No | 1 |
FANCF | P40 | TSG | No | No | No | 1 |
PTK6 | P12 | oncogene, TSG | No | No | No | 1 |
MSH6 | P20 | TSG | TSG | No | No | 1 |
SPECC1 | P45 | fusion | No | No | No | 1 |
PRKCI | P01 | No | No | No | No | 1 |
MATK | P48 | No | No | No | Yes | 1 |
ACKR3 | P50 | oncogene, fusion | No | No | No | 1 |
ERBB3 | P32 | oncogene | No | No | No | 1 |
IDH2 | P42 | oncogene | Oncogene | pancan_fre:0.80% | Yes | 1 |
FGFR3 | P13 | oncogene, fusion | Oncogene | pancan_fre:1.00% | Yes | 1 |
FGFR1 | P51 | oncogene, fusion | No | No | No | 1 |
AFF4 | P31 | oncogene, fusion | No | No | No | 1 |
MAP1 B | P08 | No | No | No | Yes | 1 |
EPB41L3 | P04 | No | No | No | Yes | 1 |
TPR | P43 | fusion | No | No | Yes | 1 |
GNAS | P19 | oncogene | Oncogene | No | Yes | 1 |
RBMX | P53 | No | No | No | Yes | 1 |
AFF1 | P06 | fusion | No | No | No | 1 |
CDKN2C | P26 | TSG | No | pancan_fre:0.20% | Yes | 1 |
WHSC1L1 | P04 | oncogene, fusion | No | No | Yes | 1 |
GOT2 | P47 | No | No | No | Yes | 1 |
LYN | P11 | No | No | No | Yes | 1 |
MGMT | P06 | TSG | No | No | No | 1 |
PMS1 | P20 | Â | No | No | No | 1 |
PMS2 | P20 | TSG | No | No | No | 1 |
LHFP | P14 | fusion | No | No | No | 1 |
AMER1 | P52 | TSG | No | No | No | 1 |
NACA | P09 | fusion | No | No | No | 1 |
FGF4 | P13 | No | No | No | No | 1 |
FGF3 | P35 | No | No | No | No | 1 |
HOXD11 | P40 | oncogene, fusion | No | No | No | 1 |
SMCHD1 | P03 | No | No | No | Yes | 1 |
JAZF1 | P19 | fusion | No | No | No | 1 |
BCOR | P40 | TSG, fusion | TSG | No | Yes | 1 |
ADAM10 | P03 | No | No | No | Yes | 1 |
G3BP1 | P09 | No | No | No | Yes | 1 |
BCL10 | P05 | TSG, fusion | No | No | No | 1 |
CDKN1B | P40 | TSG | No | pancan_fre:0.70% | Yes | 1 |
SETBP1 | P12 | oncogene, fusion | Oncogene | pancan_fre:2.20% | No | 1 |
AKT1 | P14 | oncogene | Oncogene | pancan_fre:0.90% | Yes | 1 |
PSIP1 | P50 | oncogene, fusion | No | No | No | 1 |
CCDC6 | P36 | TSG, fusion | No | No | No | 1 |
ARHGEF10 | P25 | TSG | No | No | No | 1 |
REL | P19 | oncogene | No | No | No | 1 |
COL2A1 | P17 | fusion | No | No | No | 1 |
TSC1 | P12 | TSG | TSG | No | No | 1 |
SMC3 | P26 | No | No | pancan_fre:1.20% | Yes | 1 |
ARID5B | P37 | No | No | pancan_fre:1.60% | Yes | 1 |
IGF1R | P15 | No | No | No | No | 1 |
HNF1A | P20 | TSG | TSG | No | No | 1 |
E2F3 | P26 | No | No | No | No | 1 |
ARHGEF6 | P51 | No | No | No | Yes | 1 |
CDH1 | P48 | TSG | TSG | pancan_fre:2.50% | Yes | 1 |
KIFC3 | P01 | No | No | No | Yes | 1 |
ARHGEF10L | P21 | TSG | No | No | No | 1 |
NEK8 | P17 | No | No | No | Yes | 1 |
FAM129B | P20 | No | No | No | Yes | 1 |
IL7R | P36 | oncogene | No | No | No | 1 |
MYH9 | P10 | TSG, fusion | No | No | Yes | 1 |
CYLD | P20 | TSG | TSG | No | Yes | 1 |
CASC5 | P09 | TSG, fusion | No | No | No | 1 |
NUTM1 | P48 | oncogene, fusion | No | No | No | 1 |
SOX17 | P11 | No | No | pancan_fre:0.30% | Yes | 1 |
BRCA1 | P11 | TSG | TSG | pancan_fre:1.90% | Yes | 1 |
BRCA2 | P20 | TSG | TSG | pancan_fre:2.70% | Yes | 1 |
WNK2 | P53 | TSG | No | No | No | 1 |
P4HB | P26 | No | No | No | Yes | 1 |
ARNT | P53 | oncogene, TSG, fusion | No | No | No | 1 |
BCL3 | P07 | oncogene, fusion | No | No | No | 1 |
RNF213 | P20 | fusion | No | No | Yes | 1 |
DOCK2 | P32 | No | No | No | Yes | 1 |
09-Sep | P31 | fusion | No | No | No | 1 |
05-Sep | P12 | fusion | No | No | No | 1 |
DCAF12L2 | P23 | Â | No | No | No | 1 |
NEDD4L | P20 | No | No | No | Yes | 1 |
RAP1GDS1 | P38 | oncogene, fusion | No | No | No | 1 |
RPP38 | P20 | No | No | No | Yes | 1 |
CTNND2 | P43 | oncogene | No | No | No | 1 |
ATRX | P19 | TSG | TSG | pancan_fre:2.80% | Yes | 1 |
RAD51B | P44 | TSG, fusion | No | No | No | 1 |
TP53BP1 | P20 | No | No | No | Yes | 1 |
PICALM | P20 | fusion | No | No | No | 1 |
BCL2 | P26 | oncogene, fusion | Oncogene | No | No | 1 |
ASXL2 | P40 | TSG | No | No | No | 1 |
SMC1A | P35 | TSG | No | pancan_fre:1.50% | Yes | 1 |
TLR4 | P43 | No | No | pancan_fre:1.90% | Yes | 1 |
KDM6A | P50 | oncogene, TSG | TSG | pancan_fre:2.00% | Yes | 1 |
MET | P06 | oncogene | Oncogene | No | No | 1 |
DNM3 | P36 | No | No | No | Yes | 1 |
BCL11A | P20 | oncogene, fusion | No | No | No | 1 |
GATA3 | P20 | oncogene, TSG | TSG | pancan_fre:3.20% | Yes | 1 |
RPN1 | P45 | fusion | No | No | No | 1 |
EPPK1 | P11 | No | No | pancan_fre:1.40% | Yes | 1 |
AXL | P20 | No | No | No | No | 1 |
CBL | P26 | oncogene, TSG, fusion | Oncogene | No | No | 1 |
PRDM2 | P46 | TSG | No | No | Yes | 1 |
GIGYF2 | P03 | No | No | No | Yes | 1 |
NR4A2 | P12 | No | No | No | Yes | 1 |
MITF | P38 | oncogene | No | No | No | 1 |
RPTOR | P08 | No | No | No | No | 1 |
CNOT3 | P46 | TSG | No | No | Yes | 1 |
BRD3 | P20 | oncogene, fusion | No | No | No | 1 |
SPTAN1 | P43 | No | No | No | Yes | 1 |
PPFIBP1 | P20 | fusion | No | No | No | 1 |
MKL1 | P50 | oncogene, TSG, fusion | No | No | No | 1 |
FANCD2 | P50 | TSG | No | No | No | 1 |
ZBTB16 | P06 | TSG, fusion | No | No | No | 1 |
DOCK4 | P47 | No | No | No | Yes | 1 |
SND1 | P50 | oncogene, fusion | No | No | No | 1 |
ERCC3 | P45 | TSG | No | No | No | 1 |
USP6 | P07 | oncogene, fusion | No | No | No | 1 |
HIP1 | P52 | oncogene, fusion | No | No | No | 1 |
INTS1 | P32 | No | No | No | Yes | 1 |
TGOLN2 | P38 | No | No | No | Yes | 1 |
IDH1 | P14 | oncogene | Oncogene | pancan_fre:1.50% | Yes | 1 |
PTPRK | P39 | TSG, fusion | No | No | No | 1 |
GMPS | P40 | fusion | No | No | No | 1 |
ATIC | P03 | fusion | No | No | No | 1 |
FOXA2 | P20 | No | No | pancan_fre:0.50% | Yes | 1 |
CDKN2A | P22 | TSG | TSG | pancan_fre:3.60% | Yes | 1 |
SKI | P45 | oncogene | No | No | No | 1 |
CCR7 | P11 | oncogene | No | No | No | 1 |
FOSL2 | P06 | No | No | No | Yes | 1 |
PWWP2A | P51 | fusion | No | No | No | 1 |
DDR2 | P09 | oncogene | No | No | No | 1 |
CD274 | P07 | TSG, fusion | No | No | No | 1 |
CDH17 | P32 | oncogene | No | No | No | 1 |
FANCA | P26 | TSG | No | No | Yes | 1 |
ARID1B | P38 | TSG | TSG | No | No | 1 |
NIPBL | P09 | No | No | No | Yes | 1 |
KMT2A | P19 | oncogene, fusion | No | No | No | 1 |
ANKRD6 | P01 | No | No | No | Yes | 1 |
CTNND1 | P03 | Â | No | No | Yes | 1 |
MACF1 | P11 | No | No | No | Yes | 1 |
PABPC4 | P27 | No | No | No | Yes | 1 |
PREX2 | P26 | oncogene | No | No | No | 1 |
ZNRF3 | P04 | TSG | No | No | No | 1 |
ETV1 | P20 | oncogene, fusion | No | No | No | 1 |
ETV5 | P09 | oncogene, fusion | No | No | No | 1 |
TAF1 | P06 | No | No | pancan_fre:2.30% | Yes | 1 |
HOXA11 | P14 | oncogene, TSG, fusion | No | No | No | 1 |
ABL2 | P01 | oncogene, fusion | No | No | No | 1 |
POLD1 | P20 | TSG | No | No | No | 1 |
HMGA2 | P13 | oncogene, fusion | No | No | No | 1 |
MSN | P04 | fusion | No | No | Yes | 1 |
ZRSR2 | P22 | TSG | No | No | No | 1 |