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Table 2 Grading of adverse event (AE) occurred in the 1st month*

From: Autologous stem cell transplantation in tandem with Anti-CD30 CAR T-cell infusion in relapsed/refractory CD30+ lymphoma

AE

Grade of AE in each patient

P1

P2

P3

P4

P5

P6

CRS

1

1

1

1

0

1

ICANS

0

0

0

0

0

0

Secondary infection

0

0

0

0

0

0

Hypoxia

0

0

0

0

0

0

Pulmonary edema

0

0

0

0

0

0

Hypotension

0

0

0

0

0

2

Nausea

0

0

3

0

0

2

Vomiting

0

0

2

0

0

0

Diarrhea

0

2

2

2

0

2

Oral mucositis

0

2

0

0

0

0

Purpura

0

2

0

0

0

0

Neutropenia

3

3

3

3

3

3

Anemia

1

1

1

1

1

1

Thrombocytopenia

3

3

3

3

3

3

Prolonged APTT

0

0

1

0

0

1

Hyperuricemia

1

1

0

0

0

1

Transaminitis

1

1

0

1

1

1

Hypoalbuminemia

1

1

0

1

1

1

  1. *Time calculated since CAR T-cell infusion
  2. P patient, CRS cytokine release syndrome, ICANS immune effector cell associated neurotoxicity syndrome, APTT activated partial thromboplastin time