Fig. 1

Schematic view of the genomic structure of PMP22 gene family. The boxes mark the exons. Start and stop codons are indicated. The numbers on the genes refer to exons. The italic numbers below the genes indicate the sizes of the introns and exons. The PMP22 gene generates two transcripts through alternative splicing of exons la and lb. These two transcripts are regulated by two alternative PMP22 promoters, P1 and P2