Table 1 The IC50 values of KG1a and Kasumi cells treated with Chidamide alone or in combination with Apatinib
Drugs | IC50 (uM) of KG1α | Fold | P | IC50 (uM) of Kasumi-1 | Fold | P | ||
|---|---|---|---|---|---|---|---|---|
Single | Combination | Single | Combination | |||||
Chidamide | 8.05 ± 2.13 |  |  |  | 8.37 ± 3.02 |  |  |  |
Apatinib (2.5 uM) + Chidamide |  | 6.04 ± 1.45 | 1.33 | < 0.01 |  | 6.44 ± 1.76 | 1.30 | < 0.01 |
Apatinib (5.0 uM) + Chidamide |  | 3.58 ± 1.62 | 2.25 | < 0.01 |  | 4.10 ± 1.35 | 2.04 | < 0.01 |
Apatinib (10.0 uM) + Chidamide |  | 1.99 ± 0.87 | 4.05 | < 0.01 |  | 2.03 ± 0.73 | 4.12 | < 0.01 |