| JULIET (tisagenlecleucel) efficacy analysis set [8] | TRANSCEND (liso-cel) DLBCL efficacy set [6] | Liso-cel vs tisagenlecleucel | |||
---|---|---|---|---|---|---|
n | % | n or ESS | % | OR (95% CI) | P-value | |
ORR analyses | ||||||
 Naive | 93 | 51.6 | 256 | 72.7 | 2.49 (1.52‒4.07) |  < 0.001 |
 Primary | 164 | 74.7 | 2.78 (1.63‒4.74) |  < 0.001 | ||
 Sensitivity | 37.3 | 80.8 | 3.95 (1.64‒9.51) | 0.002 | ||
CR rate analyses | ||||||
 Naive | 93 | 39.8 | 256 | 53.1 | 1.71 (1.06‒2.78) | 0.029 |
 Primary | 200.1 | 57.0 | 2.01 (1.22‒3.30) | 0.006 | ||
 Sensitivity | 37.3 | 60.6 | 2.33 (1.06‒5.10) | 0.034 |