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Table 1 Characteristics of patients with p190 and p210 in Ph + ALL

From: Distinct outcomes, ABL1 mutation profile, and transcriptome features between p190 and p210 transcripts in adult Philadelphia-positive acute lymphoblastic leukemia in the TKI era

Characteristics

p190 (n = 199)

p210 (n = 106)

p-value

Sex (n, M/F)

101/98

47/59

0.286

Age [years, M(range)]

43.0 (14.0–83.0)

46.0 (14.0–71.0)

0.130

WBC [*10E9/L, M(range)]

18.0 (0.2–403.4)

33.7 (1.0–461.9)

0.050

Hb [g/L, \(\overline{x}\) ± s]

97.7 ± 28.9

92.3 ± 28.7

0.120

PLT [*10E9/L, M(range)]

30.0 (2.0–460.0)

38.0 (2.0–403.0)

0.047

LDH [U/L, M(range)]

599.5 (134.0–7638.0)

525.5 (128.0–4187.0)

0.385

Ferritin [ng/ml, M(range)]

909.8 (37.3–88,150.0)

874.4 (13.7–10,943.1)

0.771

BM blast [%, M(range)]

86.3 (23.0–98.0)

81.0 (22.0–96.0)

0.003

Relative BCR/ABL quantification [%, M(range)]

44.0 (7.2–165.9)

77.9 (25.0–195.0)

 < 0.001

Karyotype

0.843

 With ACAs

 Without ACAs

 Unknown

51

31

94

54

54

21

  1. WBC white blood cell, Hb hemoglobin, PLT Platelet, LDH Lactate dehydrogenase, BM bone marrow, ACAs additional cytogenetic abnormalities, CNS central nervous system, TKIs tyrosine kinase inhibitors