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Table 1 Characteristics of patients with p190 and p210 in Ph + ALL

From: Distinct outcomes, ABL1 mutation profile, and transcriptome features between p190 and p210 transcripts in adult Philadelphia-positive acute lymphoblastic leukemia in the TKI era

Characteristics p190 (n = 199) p210 (n = 106) p-value
Sex (n, M/F) 101/98 47/59 0.286
Age [years, M(range)] 43.0 (14.0–83.0) 46.0 (14.0–71.0) 0.130
WBC [*10E9/L, M(range)] 18.0 (0.2–403.4) 33.7 (1.0–461.9) 0.050
Hb [g/L, \(\overline{x}\) ± s] 97.7 ± 28.9 92.3 ± 28.7 0.120
PLT [*10E9/L, M(range)] 30.0 (2.0–460.0) 38.0 (2.0–403.0) 0.047
LDH [U/L, M(range)] 599.5 (134.0–7638.0) 525.5 (128.0–4187.0) 0.385
Ferritin [ng/ml, M(range)] 909.8 (37.3–88,150.0) 874.4 (13.7–10,943.1) 0.771
BM blast [%, M(range)] 86.3 (23.0–98.0) 81.0 (22.0–96.0) 0.003
Relative BCR/ABL quantification [%, M(range)] 44.0 (7.2–165.9) 77.9 (25.0–195.0)  < 0.001
Karyotype 0.843
 With ACAs
 Without ACAs
 Unknown
51 31
94 54
54 21
  1. WBC white blood cell, Hb hemoglobin, PLT Platelet, LDH Lactate dehydrogenase, BM bone marrow, ACAs additional cytogenetic abnormalities, CNS central nervous system, TKIs tyrosine kinase inhibitors