A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis

Table 4 Expression of GPI and GPI-AP in peripheral blood cells of 12 mice

	RBC		B cells		T cells		Granulocyte
	CD24⁺	FLAER⁺	CD24⁺	FLAER⁺	CD48⁺	FLAER⁺	CD24⁺	FLAER⁺
A1	0	0	0.1	0	0.2	0	0.5	0.3
A2	0	0	0.5	0.3	0.4	0	1.4	0
A3	0	0	0	0.6	0	0.4	0.4	0
B1	2.39	2.36	54.11	55.92	22.15	22.15	37.70	33.02
B2	1.29	1.28	53.09	60.78	24.37	24.58	56.03	57.76
B3	5.18	5.10	73.30	75.41	26.82	26.22	86.0	85.6
C1	100	99.8	99.6	99.4	100	100	98.9	100
C2	99.8	100	100	100	98.9	99.2	100	99.4
C3	100	100	99.6	99.9	99.4	100	100	100
D1	99.6	99.4	100	99.2	99.3	100	100	99.6
D2	100	99.5	99.2	99.4	100	100	99.9	99.4
D3	99.9	100	99.2	100	99.2	99.2	100	99.3

A. CKO homozygous mice, B. CKO heterozygous mice, C. Flox mice, D. normal C57BL/6N mice

ISSN: 2162-3619