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Table 1 Clinicopathologic characteristics of enrolled patients

From: MET amplification identified by next-generation sequencing and its clinical relevance for MET inhibitors

Characteristic

N (%)

Age, years

 < 60

26 (65.0)

 ≥ 60

14 (35.0)

Sex

 Female

14 (35.0)

 Male

26 (65.0)

Pathology

 Adenocarcinoma

37 (92.5)

 Others

3 (7.5)

EGFR status

 Wide-type

21 (52.5)

 Mutation

19 (47.5)

MET exon 14 skipping mutations

 Yes

2 (5.0)

 No

38 (95.0)

MET amplification by FISH

 Amplified

25 (62.5)

 Non-amplified

15 (37.5)

MET amplification by NGS

 GCN  ≥ 5

10 (25.0)

 GCN  < 5

30 (75.0)

Focal amplified by NGS

 Focal amplified

16 (40.0)

 Non-focal amplified

19 (47.5)

 Not available

5 (12.5)

  1. Data are presented as n (%)
  2. GCN Gene copy number