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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: Blocking siglec-10hi tumor-associated macrophages improves anti-tumor immunity and enhances immunotherapy for hepatocellular carcinoma

Fig. 3

Intratumoral Siglec-10hi TAMs are associated with the pro-tumor immune contexture in HCC. a Comparison of inhibitory receptor gene expression level between Siglec-10 low and high group in TCGA cohort. b The number of CD8+, CD56+, CD68+, CD4+ FoxP+, and CD4+ FoxP− cells in HCC specimens with low and high Siglec-10hi TAMs infiltrating based on the results of flow cytometry analysis. Cells were pre-gated on CD45. c, d The ratio of effector molecule–positive CD8+ cells (c) and inhibitory receptor-positive CD8+ cells (d) in total CD8+ cells in HCC specimens with low and high Siglec-10hi TAM infiltration

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Experimental Hematology & Oncology

ISSN: 2162-3619

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