Fig. 4

Overall survival (OS) analysis of tumor mutation burden as estimated by a 69-gene-panel (panel-TMB) in DLBCL patients. panel-TMB was associated with poor OS in the GDPH (a) and TCGA (c) datasets. Kaplan–Meier curves between low and high panel-TMB groups (left panel). The restricted mean survival time (RMST) was determined by "survRM2" package in R (version 3.6.1, https://www.r-project.org/) (right panel). The interaction of panel-TMB and treatment options in the GDPH (b) and TCGA (d) datasets