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Table 3. Coagulation abnormalities/clinical prognostic factors and mortality

From: COVID-19-associated coagulopathy: thromboembolism prophylaxis and poor prognosis in ICU

Prognostic factors Survivors Non-survivors P value
No. % No. %
Temperaturemax (°C) 0.291
 ≥39 45 25.00 51 28.33  
 <39 46 25.56 38 21.11  
Duration of Low BP (h) 0.000*
 0 83 46.11 25 13.89  
 <72 1 0.56 25 13.89  
 ≥72 7 3.89 39 21.67  
Blood transfusion (ml) 0.037*
 0 73 40.56 55 30.56  
 ≤800 13 7.22 20 11.11  
 >800 6 3.33 13 7.22  
Lymphocyte 0.000*
 ≥1.0 × 109/L 33 18.33 7 3.89  
 <1.0 × 109/L 58 32.22 82 45.56  
Platelet count 0.001*
 ≥150 × 109/L 77 42.78 56 31.11  
 <150 × 109/L 14 7.78 33 18.33  
SIC score 0.002*
 <4 85 47.22 69 38.33  
 ≥4 6 3.33 20 11.11  
DIC score 0.000*
 <5 78 43.33 48 26.67  
 ≥5 13 7.22 41 22.78  
Overt DIC 0.000*
 Yes 4 2.22 59 32.78  
 No 87 48.33 30 16.67  
Prolongation of PT (s) 0.785
 >3 6 3.33 5 2.78  
 ≤3 85 47.22 84 46.67  
Prolongation of aPTT (s) 0.632
 >10 2 1.11 3 1.67  
 ≤10 89 49.44 86 47.78  
Fbg (g/L) 0.160
 1.5–4 32 17.78 21 11.67  
 >4 58 32.22 65 36.11  
 <1.5 1 0.56 3 1.67  
D-dimer (mg/L) 0.000*
 ≤0.5 25 13.89 1 0.56  
 >0.5 and ≤2 34 18.89 27 15.00  
 >2 and <5 13 7.22 18 10.00  
 >5 19 10.56 43 23.89  
FDP (mg/L) 0.000*
 ≤5 52 28.89 10 5.56  
 >5 and ≤20 12 6.67 21 11.67  
 >20 9 5.00 34 18.89  
Antithrombin (%) 0.147
 ≥80 20 11.11 37 20.56  
 <80 29 16.11 31 17.22  
Serum calcium levels (mmol/L) 0.002*
 ≥1.8 70 38.89 73 40.56  
 <1.8 2 1.11 16 8.89  
VTE prophylaxis 0.098
 Yes 29 16.11 39 21.67  
 No 62 34.44 50 27.78  
  1. BP blood pressure, SIC sepsis-induced coagulopathy, DIC disseminated intravascular coagulation, PT prothrombin time, aPTT activated partial thromboplastin time, Fbg fibrinogen, FDP fibrin degradation products, VTE venous thromboembolism
  2. Blood transfusion: red blood cells, platelet or fresh-frozen plasma
  3. *Statistically significant