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Table 2 Exposure to treatment and compliance

From: Two-year long safety and efficacy of deferasirox film-coated tablets in patients with thalassemia or lower/intermediate risk MDS: phase 3 results from a subset of patients previously treated with deferasirox in the ECLIPSE study

 

Deferasirox FCT, N = 53

Duration of exposure (days), mean (SD)

571.5 (215.28)

Duration of exposure categories (weeks), n (%)

 < 24

6 (11.3)

 24 to < 52

4 (7.5)

 52 to < 72

8 (15.1)

 72 to < 100

11 (20.8)

 ≥ 100

24 (45.3)

Patient treatment years

82.9

Average actual dose (mg/kg/day), mean (SD)

21.3 (4.63)

Average actual dose category (mg/kg/day), n (%)

 < 10.5

1 (1.9)

 10.5 to < 17.5

10 (18.9)

 17.5 to < 24.5

27 (50.9)

 ≥ 24.5

15 (28.3)

Compliance

 Relative consumed tablet count (%), mean (SD)

90.2 (10.07)

Persistence

 Continuous use of deferasirox FCT with no interruption for ≥ 60 days, n (%)

  Up to 3 months (n = 53)

53 (100.0)

  Up to 6 months (n = 51)

51 (100.0)

  Up to 9 months (n = 47)

47 (100.0)

  Up to 12 months (n = 46)

46 (100.0)

 Continuous use of deferasirox FCT with no interruption for ≥ 30 days, n (%)

  Up to 3 months (n = 53)

52 (98.1)

  Up to 6 months (n = 51)

50 (98.0)

  Up to 9 months (n = 47)

46 (97.9)

  Up to 12 months (n = 46)

44 (95.7)

  1. FCT film-coated tablet, SD standard deviation