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Table 1 The incidence and its trends of leukemia, by sex, age, type, and region, between 1990 and 2017

From: Leukemia incidence trends at the global, regional, and national level between 1990 and 2017

 

1990

2017

1990-2017

Case number (\(\times 1000\))

ASIR (/105)

Case number (\(\times 1000\))

ASIR (/105)

EAPC (95% CI)

Overall

354.5

7.42

518.5

6.76

− 0.43 (− 0.48, − 0.38)

Sex

 Male

191.3

8.48

295.4

8.09

− 0.26 (− 0.32, − 0.21)

 Female

163.1

6.57

223.1

5.62

− 0.65 (− 0.70, − 0.60)

Age (years)a

 Under 5

54.4

8.44

52.9

7.78

− 0.12 (− 0.20, − 0.05)

 5–14

50.6

4.51

45.5

3.51

− 1.18 (− 1.38, − 0.98)

 15–49

102.4

3.74

123.1

3.15

− 0.89 (− 1.00, − 0.77)

 50–69

80.0

11.64

149.7

11.36

− 0.24 (− 0.33, − 0.15)

 70+

67.0

32.96

147.3

34.03

0.11 (0.08, 0.14)

Types

 ALL

49.1

0.89

64.2

0.85

− 0.08 (− 0.15, − 0.02)

 CLL

38.0

0.99

90.6

1.15

0.46 (0.40, 0.52)

 AML

63.8

1.35

119.6

1.54

0.56 (0.49, 0.62)

 CML

31.8

0.75

34.2

0.43

− 2.40 (− 2.53, − 2.26)

 Others

171.8

3.43

209.9

2.78

− 0.93 (− 1.02, − 0.84)

SDI region

 High

106.6

9.10

150.8

7.73

− 0.67 (− 0.74, − 0.60)

 High-middle

80.4

7.59

123.7

8.68

0.56 (0.50, 0.63)

 Middle

93.2

6.57

131.9

6.47

− 0.19 (− 0.34, − 0.04)

 Low-middle

44.4

4.87

66.8

4.54

− 0.34 (− 0.40, − 0.28)

 Low

27.9

4.68

42.6

4.14

− 0.55 (− 0.59, − 0.50)

GBD region

 Andean Latin America

2.1

6.00

3.5

5.97

0.12 (− 0.01, 0.26)

 Australasia

3.0

13.38

4.2

9.62

− 1.65 (− 1.92, − 1.38)

 Caribbean

2.1

6.72

2.8

5.82

− 0.59 (− 0.68, − 0.50)

 Central Asia

3.5

5.17

4.0

4.74

− 0.20 (− 0.31, − 0.08)

 Central Europe

9.1

6.71

11.1

6.37

0.02 (− 0.12, 0.17)

 Central Latin America

9.1

6.39

14.5

5.89

− 0.32 (− 0.38, − 0.27)

 Central sub-Saharan Africa

1.8

4.07

3.4

3.87

− 0.24 (− 0.27, − 0.20)

 East Asia

102.3

8.49

147.7

10.54

0.83 (0.63, 1.02)

 Eastern Europe

17.1

7.00

19.7

6.91

0.06 (− 0.08, 0.21)

 Eastern sub-Saharan Africa

7.2

4.66

13.3

4.48

− 0.29 (− 0.38, − 0.20)

 High-income Asia Pacific

11.3

6.22

17.8

5.27

− 0.47 (− 0.57, − 0.38)

 High-income North America

27.4

8.17

39.6

7.17

− 0.61 (− 0.78, − 0.43)

 North Africa and Middle East

19.3

7.08

32.3

6.37

− 0.24 (− 0.31, − 0.17)

  Oceania

0.3

6.61

0.6

6.34

− 0.07 (− 0.11, − 0.03)

 South Asia

40.7

4.24

62.0

3.99

− 0.30 (− 0.39, − 0.22)

 Southeast Asia

24.2

6.26

38.9

6.37

0.07 (− 0.04, 0.19)

 Southern Latin America

3.0

6.25

3.9

5.29

− 0.68 (− 0.75, − 0.61)

 Southern sub-Saharan Africa

1.6

4.36

2.5

4.10

− 0.30 (− 0.69, 0.08)

 Tropical Latin America

7.2

5.50

10.2

4.65

− 0.58 (− 0.67, − 0.49)

 Western Europe

56.8

10.62

75.7

8.86

− 0.76 (− 0.83, − 0.69)

 Western sub-Saharan Africa

5.3

3.44

10.8

3.40

− 0.14 (− 0.23, − 0.05)

  1. ASIR age-standardized incidence rate, EAPC estimated average percentage change, SDI socio-demographic index, ALL acute lymphoblastic leukemia, CLL chronic lymphoblastic leukemia, AML acute myeloid leukemia, CML chronic myeloid leukemia
  2. aThe incidence rates for each age group were crude incidence rather than the age-standardized incidence