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Table 5 Factors of affecting 5-year cumulative survival rate between MSD and AD

From: Alternative donor peripheral blood stem cell transplantation for the treatment of high-risk refractory and/or relapsed childhood acute leukemia: a randomized trial

Variables 5-year cumulative OS 5-year cumulative DFS
MSD AD MSD AD
Grade II-IV aGVHD
 Yes 50.0 ± 35.4 30.0 ± 17.5 50.0 ± 35.4 15.0 ± 13.8
 No 54.4. ± 9.0 78.1 ± 6.7 44.4 ± 9.3 73.6 ± 7.1
 P-value 0.474 0.002 0.605 0.001
Donor-recipient ABO compatibility
 Compatible 66.6 ± 12.8 55.6 ± 11.4 67.0 ± 12.8 50.9 ± 11.6
 Incompatible 45.9 ± 11.3 83.0. ± 7.1 27.7 ± 10.9 74.9. ± 8.5
 P-value 0.244 0.047 0.041 0.078
Conditioning regimen
 Bu/Cy-based 52.3 ± 10.3 77.6 ± 7.1 44.1 ± 10.4* 69.2 ± 7.9*
 TBI/Cy-based 60.8 ± 15.8 58.7. ± 13.1 40.5 ± 19.6* 58.7 ± 13.1*
 P-value 0.777 0.023 0.854 0.093
CMV infection
 Yes 44.4 ± 18.9 60.9 ± 9.5 15.6 ± 14.2* 57.4 ± 9.7*
 No 57.2 ± 9.7 85.0. ± 8.2 54 ± 9.8* 75 ± 9.9*
 P-value 0.748 0.033 0.235 0.083
  1. * Estimated value censored