Table 1 Characteristics of all patients between MSD and AD
Variables | MSD(n = 42) | AD(n = 69) | χ2 | P value |
|---|---|---|---|---|
Gender (n, %) | 0.172 | 0.678 | ||
 Male | 27 (64.3) | 47 (68.1) | ||
 Female | 15 (35.7) | 22 (31.9) | ||
Primary disease (n, %) | 0.016 | 0.899 | ||
 AML | 22 (52.4) | 37 (53.6) | ||
 ALL | 20 (47.6) | 32 (46.4) | ||
Disease status at HSCT (n, %) | 1.873 | 0.392 | ||
 First CR | 19 (45.2) | 39 (56.5) | ||
 Second and other CR | 16 (38.1) | 18 (26.1) | ||
 Relapse | 7 (16.7) | 12 (17.4) | ||
Disease status at HSCT (n, %) | 1.332 | 0.248 | ||
 First CR | 19 (45.2) | 39 (56.5) | ||
 Other | 23 (54.8) | 30 (43.5) | ||
Extramedullary infiltration (n, %) | 2.538 | 0.111 | ||
 Yes | 8 (19.0) | 6 (8.7) | ||
 No | 34 (81.0) | 63 (91.3) | ||
Conditioning regimen (n, %) | 0.082 | 0.775 | ||
 Bu/Cy-based | 30 (71.4) | 51 (73.9) | ||
 TBI/Cy-based | 12 (28.6) | 18 (26.1) | ||
Gender of donor-recipient (n, %) | 5.669 | 0.017 | ||
 Identical | 19 (45.2) | 47 (68.1) | ||
 Different | 23 (54.8) | 22 (31.9) | ||
Donor-recipient ABO compatibility (n, %) | 0.014 | 0.907 | ||
 Compatible | 19 (45.2) | 32 (46.4) | ||
 Incompatible | 23 (54.8) | 37 (53.6) | ||
Abnormal markers | NA | NA | ||
 t(9;22) | 8 (19.0) | 13 (18.8) | ||
 MLL/AF4 | 1 (2.4) | 3 (4.3) | ||
 FLT3/ITD | 2 (4.8) | 1 (1.4) | ||
MRD | 0.014 | 0.906 | ||
 Yes | 12 (28.6) | 19 (27.5) | ||
 No | 30 (71.4) | 50 (72.5) | ||
MNC (× 108/kg) | 11.74 (3.98–31.03) | 14.57 (3.57–47.11) | NA | NA |
CD34 + cells(× 106/kg) | 5.84 (3.43–23.30) | 8.33 (3.07–35.7) | NA | NA |
Time for implantation of neutrophils (d) | 12 (9–19) | 13 (10–26) | NA | NA |
Time for implantation of PLT(d) | 13 (8–30) | 13 (9–26) | NA | NA |