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Table 2 Clinical manifestations and cytogenetic abnormalities of AML patients stratified by age groups

From: Gene mutational analysis by NGS and its clinical significance in patients with myelodysplastic syndrome and acute myeloid leukemia

 Total patients (n = 325)Younger AML patients (n = 258)Older AML patients (n = 57)p value
Age46 (16–87)43 (16–59 years)69 (60–87 years)N/A
Gender males (n, %)164 (53.8%)134 (53.4%)30 (55.6%)0.772
WBC (×109/L) (mean, range)37.3 (0.1–450.7)36.5 (0.1–450.7)39.7 (0.5–316.1)0.724
Hb (g/L) (mean, range)78.6 (3.3–138.5)78.0 (3.3–135)81.0 (39–138.5)0.384
Plate (×109/L) (mean, range)63.5 (2.0–442)63.1 (2.0–442.0)65.6 (3.0–376.0)0.814
Blast in BM (mean, range)57.4 (20.0–97.2)58.1 (20.0–97.2)54.3 (22–93.2)0.275