Temporality of heparin-induced antibodies: a retrospective study in outpatients undergoing hemodialysis on unfractionated heparin

Table 3 Prevalence of thrombosis risk factors at baseline and thrombotic events during follow up, classed according to HIA status

	Overall (%)	HIA negative (OD < 0.400) (%)	HIA positive (OD ≥ 0.400) (%)	HIA weak positive (OD 0.400–1.000) (%)	HIA positive and HNP > 50% (%)	HIA strong positive (OD ≥ 1.000) (%)
History of AVTE (baseline)^a	12.75	14.10	10.00	8.50	12.12	18.20
History of cancer	8.51	9.20	7.10	6.80	3.03	9.10
Hypercoagulable state^b	8.44	9.10	7.10	8.50	6.10	0.00
Obesity (BMI > 30 kg/m²)	54.67	58.40	47.10	47.50	39.40	45.40
Major surgery or pregnancy during follow up	1.87	2.10	1.40	1.70	0.00	0.00
Subsequent AVTE	32.07	32.40	31.40	30.50	30.30	36.40
Subsequent vascular access thrombosis^c	18.87	19.00	18.60	16.90	12.12	27.30

^aIncluding vascular access occlusion (1 event in a HIA negative case), provoked and unprovoked events
^bKnown diagnosis of inherited or acquired thrombophilia (antiphospholipid syndrome, essential thrombocythemia, polycythemia vera, protein C/S deficiency); HbSS; amyloidosis; chronic use of medications associated with thrombosis; chronic inflammatory states
^cExcluding central venous catheter thrombosis

ISSN: 2162-3619