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Table 3 Prevalence of thrombosis risk factors at baseline and thrombotic events during follow up, classed according to HIA status

From: Temporality of heparin-induced antibodies: a retrospective study in outpatients undergoing hemodialysis on unfractionated heparin

  Overall (%) HIA negative (OD < 0.400) (%) HIA positive (OD ≥ 0.400) (%) HIA weak positive (OD 0.400–1.000) (%) HIA positive and HNP > 50% (%) HIA strong positive (OD ≥ 1.000) (%)
History of AVTE (baseline)a 12.75 14.10 10.00 8.50 12.12 18.20
History of cancer 8.51 9.20 7.10 6.80 3.03 9.10
Hypercoagulable stateb 8.44 9.10 7.10 8.50 6.10 0.00
Obesity (BMI > 30 kg/m2) 54.67 58.40 47.10 47.50 39.40 45.40
Major surgery or pregnancy during follow up 1.87 2.10 1.40 1.70 0.00 0.00
Subsequent AVTE 32.07 32.40 31.40 30.50 30.30 36.40
Subsequent vascular access thrombosisc 18.87 19.00 18.60 16.90 12.12 27.30
  1. aIncluding vascular access occlusion (1 event in a HIA negative case), provoked and unprovoked events
  2. bKnown diagnosis of inherited or acquired thrombophilia (antiphospholipid syndrome, essential thrombocythemia, polycythemia vera, protein C/S deficiency); HbSS; amyloidosis; chronic use of medications associated with thrombosis; chronic inflammatory states
  3. cExcluding central venous catheter thrombosis