Table 1 Clinical characteristics of patients administered bosutinib

Total number

10

15

Female: male

5:5

8:7

Age (year)

63.0 (34.0–78.0)

55.0 (19.0–81.0)

Phase, CP: AP: BP

7:2:1

15:0:0

Reason of taking bosutinib, TKI-R: TKI-Int: de novo CML

4:5:1

9:6:0

Body weight (kg)

59.9 (40.8–69.1)

53.0 (44.1–86.3)

Laboratory test values

 White blood cell (*10³/mm³)

8.5 (3.6–190.7)

6.1 (1.3–13.8)

 Hemoglobin (g/dL)

10.3 (8.2–14.2)

12.1 (8.3–14.8)

 Platelet (*10⁴/mm³)

29.5 (12.1–326.0)

19.4 (12.8–162.0)

 Aspartate transaminase (IU/L)

23.0 (14.0–56.0)

24.0 (10.0–47.0)

 Alanine transaminase (IU/L)

17.5 (9.0–65.0)

23.0 (7.0–34.0)

 Serum albumin (g/dL)

4.1 (3.7–4.3)

4.2 (3.0–5.2)

 Total bilirubin (mg/dL)

0.6 (0.2–0.9)

0.6 (0.3–2.7)

 Serum creatinine (mg/dL)

0.8 (0.5–0.9)

0.7 (0.4–1.7)

 Lipase (IU/L)

21.5 (5.0–75.0)

18.0 (6.0–38.0)