Fig. 4

Correlation of molecular and morphological responses over time in selected patients. Patients with a sustained BM-CR (MF-0). Blue arrows indicate time on active therapy. The number in the top left upper corner represents the patient # from Table 2. The red line indicates the JAK2 allele burden over time (missing in TN patients). The box in the bottom right corner shows the change in BM and response, NEG MPN = no signs of ET or PV, normal BM. The gray square represents the time of loss of HR (shown only in patients who lost their HR)