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Table 1 Clinical and demographic data from the study patients

From: Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis

Patient Age (years) Gender Genotype Avascular necrosis Previous VOC/monthb
1 20 M HbSS Bilateral femoral heads 8
2 22 F HbSC No 1.3
3 25 F HbSS Right femoral head 4
4 20 F HbSS Bilateral femoral and humeral heads 1.3
5 20 F HbSS No 3
6a 32 M HbSS Bilateral femoral heads, right humeral head 19.3
7 21 M HbSS Right femoral head 2
8a 32 M HbSS Bilateral femoral and humeral heads 3.3
9 23 M HbSC Left femoral head 2.6
10 25 M HbSS No 7
11 18 M HbSS No 3.6
12 24 M HbSS No 3.3
13 24 F HbSC No 4.3
14 28 M HbSS No 5
  1. aPatients with hip joint replacement
  2. bVOC frequency was calculated from the trimester preceding the study recruitment