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Table 1 Clinical and demographic data from the study patients

From: Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis

Patient

Age (years)

Gender

Genotype

Avascular necrosis

Previous VOC/monthb

1

20

M

HbSS

Bilateral femoral heads

8

2

22

F

HbSC

No

1.3

3

25

F

HbSS

Right femoral head

4

4

20

F

HbSS

Bilateral femoral and humeral heads

1.3

5

20

F

HbSS

No

3

6a

32

M

HbSS

Bilateral femoral heads, right humeral head

19.3

7

21

M

HbSS

Right femoral head

2

8a

32

M

HbSS

Bilateral femoral and humeral heads

3.3

9

23

M

HbSC

Left femoral head

2.6

10

25

M

HbSS

No

7

11

18

M

HbSS

No

3.6

12

24

M

HbSS

No

3.3

13

24

F

HbSC

No

4.3

14

28

M

HbSS

No

5

  1. aPatients with hip joint replacement
  2. bVOC frequency was calculated from the trimester preceding the study recruitment