Fig. 4

Cumulative costs per life-month gained. 1 Drug unit costs (as of March 2015) were based on the WAC from RED BOOK online^®. 2 First-line ipilimumab long-term overall survival and average patient weight (78.7 kg) were based on individual patient data used in Schadendorf et al. [18]. Drug cost for 10 mg/kg dose was assumed to be the same as 3 mg/kg. The total cost of ipilimumab (1 dose every 3 weeks, 4 doses in total) was incurred during the first half year since drug initiation