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Figure 4 | Experimental Hematology & Oncology

Figure 4

From: Pharmacologically relevant doses of valproate upregulate CD20 expression in three diffuse large B-cell lymphoma patients in vivo

Figure 4

Serum valproate levels and fold change in epigenetic biomarkers of surrogate tissue. (A) Serum valproate levels in response to 48-hour treatment of valproate. (B-D) Fold change of H3K9ac, H3K4me3 and HDAC2 expression in PBMCs as judged by Western blot. Blots were quantified by normalising the epigenetic biomarker to the corresponding GAPDH expression and fold change determined by normalisation to Day 0 sample. Samples are from cycle 1, 3 and 6.

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Experimental Hematology & Oncology

ISSN: 2162-3619

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