Successful treatment of a Caucasian case of multifocal Castleman’s disease with TAFRO syndrome with a pathophysiology targeted therapy - a case report

Table 1 Patient and disease characteristics at onset

Somatic features	Caucasian female, 21 years old
Genetic features and family history	Negative
Past medical history	Isolated seizure in childhood (age 15)
Past medical history	Car accident with right femur fracture (age 17)
Signs and symptoms at onset	Fever (38.5°C) with shiver
	Asthenia
	General malaise
	Pharyngodynia
	Left subcostal pain
	Dyspnea
	Periorbital edema
Abnormal laboratory data at onset	White blood cells 11.8 × 10³/μL
	Hemoglobin 11.5 g/dL
	Platelet counts 29 × 10³/μL
	AST 56 IU/L
	Albumin 1.86 g/dL
	Proteinuria 0.47 g/24 h
	CRP 22.2 mg/dL
	Ferritin 715 ng/mL

Reference ranges and abbreviations. White blood cells: 4–10 × 10³/μL; Hemoglobin: 11.5-16 g/dL; Platelet counts: 150-400 × 10³/μL; AST (aspartate aminotransferase): 0–40 IU/L; Albumin: 3.7-5.5 g/dL; Proteinuria: < 0.15 g/24 h; CRP (C reactive protein): 0–0.6 mg/dL; Ferritin 12–180 ng/mL.

ISSN: 2162-3619