Figure 2

Effect of rituximab (RTX) and 2-CdA alone or in combination (combo) on lymphoma cell lines in vitro. Cell viability was measured by 0.4% trypan blue exclusion assay over a 72 h incubation period [mean and standard error means (SEM)]. Cell lines used were: (A) WSU-FSCCL (follicular lymphoma); (B) WSU-DLCL2 (diffuse large B-cell lymphoma); and (C) WSU-WM (Waldenström’s macroglobulinemia). Cells were exposed to each agent at the beginning of culture (time 0) with 2-CdA at 50 nM, RTX 100 μg, or both agents at the same concentration. *indicates significant difference compared with control (p < 0.05).