Table 4 Multivariate analysis in the validation cohort for OS using Cox Proportional Hazard model
From: A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC
Variable | p-value | HR | 95% CI |
|---|---|---|---|
BAALC | 0.1 | 1.42 | 0.93–2.15 |
EVI1 | 0.019 | 2.21 | 1.14–4.27 |
CEBPA-dm | 0.052 | 0.36 | 0.13–1.01 |
NPM1-ABD | 0.21 | 0.76 | 0.50–1.17 |
FLT3-ITD | 0.017 | 1.64 | 1.09–2.46 |
age in years (continuous variable, in yrs) | 0.021 | 1.02 | 1.00–1.03 |
gender | 0.76 | 1.06 | 0.73–1.55 |
White blood Cell Count at diagnosis [×10^9/l] | 0.17 | 1.00 | 1.00–1.00 |
Percentage of blast cells in bone marrow | 0.45 | 1.00 | 0.99–1.00 |
Platelets at diagnosis [×10^9/l] | 0.24 | 1.00 | 1.00–1.00 |