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Table 1 Hazard ratio and logrank (p-value) for evaluated cut points in training, verification and validation datasets

From: A standardized microarray assay for the independent gene expression markers in AML: EVI1 and BAALC

Gene name

Dataset

AMLprofiler

25 thpercentile

50 thpercentile

75 thpercentile

BAALC

Training

.48 (.001)

.44 (< .001)

.63 (.01)

.43(< .001)

Verification *)

.60 (.002)

.55 (.001)

.66(.005)

.65 (.007)

Validation

.69 (.021)

.72 (.066)

.88 (.24)

.93 (.345)

ERG

Training

No significant cutoff point

1.41 (.066)

1.37 (.051)

1.45 (.048)

Verification *)

ND

1.41 (.037)

1.56 (.003)

1.72 (.001)

Validation

ND

1.54 (.02)

1.12 (.248)

1.28 (.099)

MN1

Training

2.19 (< .001)

2.56 (< .001)

1.79 (.002)

1.79 (.003)

Verification *)

1.31 (.049)

1.12 (.26)

1.32 (.049)

1.39 (.035)

Validation

1.14 (.2329)

1.37 (.068)

1.19 (.167)

1.32 (.081)

  1. OS logrank p < 0.05 indicated in bold. For ERG no cut point was identified in the training cohort.
  2. *) this data set contains only normal karyotype cases.
  3. ND, not done because lack of significant cutoff point in training.