Table 2 Univariate and multivariate analyses for CR, OS, and DFS in 48 patients with T-ALL

CR

miR-221 expression (low vs high)

0.63

0.17

2.39

0.507

1.71

0.26

10.9

0.571

WBC counts (≤ 30×10⁹/L vs > 30×10⁹/L)

1.55

0.32

7.41

0.581

0.92

0.11

7.15

0.94

Age at diagnosis (≤ 15 vs > 15)

1.68

0.43

6.54

0.454

2.63

0.53

12.9

0.234

CD56 expression (CD56^- vs CD56⁺)

0.33

0.08

1.38

0.133

0.14

0.01

1.2

0.073

OS

miR-221 expression (low vs high)

3.17

1.45

6.92

0.004

2.31

0.92

5.81

0.074

WBC counts (≤ 30x10⁹/L vs > 30×10⁹/L)

0.69

0.29

1.64

0.412

1.41

0.53

3.7

0.481

Age at Diagnosis (≤ 15 vs > 15)

2.19

0.98

4.85

0.05

2.2

0.96

5

0.059

CD56 expression (CD56^- vs CD56⁺)

2.99

1.37

6.51

0.006

2.04

0.76

5.46

0.155

DFS

miR-221 expression (low vs high)

1.87

0.89

3.92

0.093

1.54

0.57

4.17

0.391

WBC counts (≤ 30×10⁹/L vs > 30×10⁹/L)

1.76

0.81

3.82

0.148

1.81

0.65

5.01

0.25

Age at diagnosis (≤ 15 vs > 15)

0.77

0.37

1.6

0.488

0.89

0.42

1.9

0.778

CD56 expression (CD56^- vs CD56⁺)

2.73

1.03

7.18

0.041

2.25

0.69

7.28

0.173