Skip to main content

Articles

Page 3 of 13

  1. WDR5 is a highly conserved protein that performs multiple scaffolding functions in the context of chromatin. However, efforts to understand the function of WDR5 in normal tissues physiologically are quite limi...

    Authors: Lulu Liu, Yanjia Fang, Xiaodan Ding, Weihua Zhou, Remi Terranova, Yan Zhang and He Wang
    Citation: Experimental Hematology & Oncology 2023 12:39
  2. Sustained activation of hepatocyte growth factor (HGF)/c-MET signaling is a major driver of hepatocellular carcinoma (HCC) progression, but underlying mechanism is unclear. ArfGAP With SH3 Domain, Ankyrin Repe...

    Authors: Xiao-Lu Ma, Yan-Yan Nie, Su-Hong Xie, Hui Zheng, Ying Tong, Yan-Chun Wang, Tian-Qing Yan, Xin Meng, Jia-Zhen Cao, Wei-Guo Tang, Lin Guo and Ren-Quan Lu
    Citation: Experimental Hematology & Oncology 2023 12:38
  3. Surgical intervention is the first-line treatment in well-selected hepatocellular carcinoma (HCC) patients. However, only a few patients are suitable to receive radical surgery. We conducted a systematic revie...

    Authors: Po-Lung Cheng, Ping-Hsiu Wu, We-Yu Kao, Yen-Ting Lai, Jason C. Hsu, Jeng-Fong Chiou, Meng-Huang Wu and Hsin-Lun Lee
    Citation: Experimental Hematology & Oncology 2023 12:37
  4. Relapse is a major limitation of chimeric antigen receptor (CAR) T-cell therapy. Here, we speculated that decitabine (DAC) in combination with fludarabine and cyclophosphamide (FC) as a lymphodepletion regimen...

    Authors: Yunju Ma, Haiping Dai, Qingya Cui, Sining Liu, Liqing Kang, Xiaying Lian, Wei Cui, Jia Yin, Lingling Liu, Mengjie Cai, Lei Yu, Depei Wu and Xiaowen Tang
    Citation: Experimental Hematology & Oncology 2023 12:36
  5. Circulating monocytic myeloid-derived suppressive cells (M-MDSCs) are implicated as a poor prognostic factor and cause CAR T-cell failure in diffuse large B-cell lymphoma (DLBCL). Triggering receptors expresse...

    Authors: Hao-Yuan Wang, Fu-Chen Yang, Ching-Fen Yang, Yao-Chung Liu, Po-Shen Ko, Chien-Jung Li, Chun-Kuang Tsai, Yi-Lin Chung and Nien-Jung Chen
    Citation: Experimental Hematology & Oncology 2023 12:35
  6. Tumor development relies on a complex and aberrant tissue environment in which cancer cells receive the necessary nutrients for growth, survive through immune escape, and acquire mesenchymal properties that me...

    Authors: Xian-Miao Li, Zhen-Yu Zhao, Xiao Yu, Qi-Dong Xia, Peng Zhou, Shao-Gang Wang, Huan-Lei Wu and Jia Hu
    Citation: Experimental Hematology & Oncology 2023 12:34
  7. Genetic heterogeneity poses a great challenge to the understanding and management of acute myeloid leukemia (AML). Knowledge of the IKZF1 mutation in AML specifically is extremely limited. In a previous work, we ...

    Authors: Xiang Zhang, Aijie Huang, Lixia Liu, Jiayue Qin, Chengcheng Wang, Min Yang, Yinjun Lou, Lei Wang, Xiong Ni, Xiaoxia Hu, Gusheng Tang, Mengmeng Zhang, Shanbo Cao, Liping Mao, Jiejin Qian, Weilai Xu…
    Citation: Experimental Hematology & Oncology 2023 12:33
  8. Primary mediastinal (thymic) large B-cell lymphoma (PMBCL) is a rare, aggressive subtype of non-Hodgkin lymphoma and has a complex inflammatory microenvironment. Although most patients can be cured with standa...

    Authors: Raphael E. Steiner, Edwin R. Parra, Francisco Vega, Lei Feng, Jason R. Westin, Sattva S. Neelapu, Paolo Strati, Michael R. Green, Christopher R. Flowers, Luisa M. Solis, Ignacio I. Wistuba, Sairah Ahmed, Ranjit Nair, Fredrick B. Hagemeister, Mansoor Noorani and Mario L. Marques-Piubelli
    Citation: Experimental Hematology & Oncology 2023 12:32
  9. Endoplasmic reticulum stress (ER stress) may destroy endoplasmic reticulum homeostasis (ER homeostasis) and leads to programmable cell death. Unfolded protein response (UPR) originally stimulated by ER stress ...

    Authors: Xiaoting Liang, Jieyu Liu, Xingyuan Liu, Yi Jin, Minna Xu, Zhenyu Han, Ke Wang, Chunting Zhang, Fei Zou and Liang Zhou
    Citation: Experimental Hematology & Oncology 2023 12:31
  10. Melanoma is the deadliest form of skin cancer showing rising incidence over the past years. New insights into the mechanisms of melanoma progression contributed to the development of novel treatment options, s...

    Authors: Tamara Steinfass, Juliane Poelchen, Qian Sun, Giovanni Mastrogiulio, Daniel Novak, Marlene Vierthaler, Sandra Pardo, Aniello Federico, Laura Hüser, Thomas Hielscher, Rafael Carretero, Rienk Offringa, Peter Altevogt, Viktor Umansky and Jochen Utikal
    Citation: Experimental Hematology & Oncology 2023 12:29
  11. Cell cycle dysregulation characterized by cyclin D1 overexpression is common in mantle cell lymphoma (MCL), while mitotic disorder was less studied. Cell division cycle 20 homologue (CDC20), an essential mitot...

    Authors: Yingtong Chen, Ping Yang, Jing Wang, Shuang Gao, Shiyu Xiao, Weilong Zhang, Mingxia Zhu, Yanfang Wang, Xiaoyan Ke and Hongmei Jing
    Citation: Experimental Hematology & Oncology 2023 12:28
  12. As significant posttranslational modifications, ubiquitination and deubiquitination, whose balance is modulated by ubiquitin-conjugating enzymes and deubiquitinating enzymes (DUBs), can regulate many biologica...

    Authors: Xiaoya Ren, Menglong Jiang, Peng Ding, Xiaoyan Zhang, Xin Zhou, Jian Shen, Dong Liu, Xiaolong Yan and Zhiqiang Ma
    Citation: Experimental Hematology & Oncology 2023 12:27
  13. The persistence of tumor load in multiple myeloma (MM) lead to relapse in patients achieving complete remission (CR). Appropriate and effective methods of myeloma tumor load monitoring are important for guidin...

    Authors: Zhao-Yun Liu, Nan-Hao Meng, Pan-Pan Cao, Feng-Ping Peng, Jing-Yi Luo, Hao Wang, Feng-Juan Jiang, Jin Lu and Rong Fu
    Citation: Experimental Hematology & Oncology 2023 12:26
  14. Normal karyotype acute myeloid leukemia (NK-AML) is a heterogeneous hematological malignancy that contains a minor population of self-renewing leukemia stem cells (LSCs), which complicate efforts to achieve lo...

    Authors: Wenqi Wu, Zeyan Shi, Zhongyuan Tang, Huiqun Li, Xiaoke Huang, Xiaolin Liang, Jing Li, Yibin Yao, Weihua Zhao, Meiqing Wu, Jun Luo and Zhenfang Liu
    Citation: Experimental Hematology & Oncology 2023 12:25
  15. Hyperproliferative diseases such as Chronic Lymphocytic Leukemia (CLL) and Systemic Lupus Erythematosus (SLE) are potentially related to some disturbance in the apoptosis pathway, specifically in B-1a cells (CD5+

    Authors: Olívia F Souza, Vivian C de Oliveira, Gabriel J. F. Rodrigues, Lucas V. S. Costa, Fernanda Corado and Ana F. Popi
    Citation: Experimental Hematology & Oncology 2023 12:24
  16. More effective targeted therapy and new combination regimens are needed for Acute myeloid leukemia (AML), owing to the unsatisfactory long-term prognosis of the disease. Here, we investigated the synergistic e...

    Authors: Siyu Gu, Yue Hou, Katarina Dovat, Sinisa Dovat, Chunhua Song and Zheng Ge
    Citation: Experimental Hematology & Oncology 2023 12:23
  17. Lung adenocarcinoma (LUAD) is a major cause of cancer-related death worldwide, and the roles of complement-related genes in it have not been thoroughly investigated yet. In the study, we aimed to systemically ...

    Authors: Lin Zhang, Yannan Yang, Weihao Lin, Fei Shao, Yibo Gao and Jie He
    Citation: Experimental Hematology & Oncology 2023 12:22
  18. Leukemogenic SHP2 mutations occur in 35% of patients with juvenile myelomonocytic leukemia (JMML), a rare but fatal hematopoietic malignancy without representative cell models, which are urgently needed to inv...

    Authors: Yuming Zhao, Chunxiao He, Dengyang Zhang, Yao Guo, Zhiyong Peng, Liuting Yu, Na Li, Chun Chen, Zhizhuang Joe Zhao and Yun Chen
    Citation: Experimental Hematology & Oncology 2023 12:20
  19. Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a refractory and recurrent subtype of B-cell ALL enriched with kinase-activating rearrangements. Incomplete understanding of the heter...

    Authors: Xuehong Zhang, Zhijie Hou, Dan Huang, Furong Wang, Beibei Gao, Chengtao Zhang, Dong Zhou, Jiacheng Lou, Haina Wang, Yuan Gao, Zhijie Kang, Ying Lu, Quentin Liu and Jinsong Yan
    Citation: Experimental Hematology & Oncology 2023 12:19
  20. Waldenström’s macroglobulinemia (WM) is an uncommon lymphoproliferative disorder, and the precise cellular landscape and the mechanisms of progression from IgM monoclonal gammopathy of undetermined significanc...

    Authors: Yu Qiu, Xiao-shuang Wang, Yuan Yao, Yan-min Si, Xue-zhu Wang, Ming-nan Jia, Dao-bin Zhou, Jia Yu, Xin-xin Cao and Jian Li
    Citation: Experimental Hematology & Oncology 2023 12:18
  21. Hypoxia is a hallmark of cancer, and is closely intertwined with tumor immune evasion. Circular RNAs (circRNAs) have been implicated in tumor response to immune checkpoint blockades. However, hypoxia-associate...

    Authors: Zhi-Qiang Chen, Xue-Liang Zuo, Juan Cai, Yao Zhang, Guo-Yong Han, Long Zhang, Wen-Zhou Ding, Jin-Dao Wu and Xue-Hao Wang
    Citation: Experimental Hematology & Oncology 2023 12:17
  22. Hetrombopag, a small molecular thrombopoietin-receptor agonist, has shown encouraging efficiency in immunosuppressive therapy refractory or relapsed severe aplastic anaemia. To investigate the response rate of...

    Authors: Wenrui Yang, Xin Zhao, Xu Liu, Youzhen Xiong, Huihui Fan, Li Zhang, Jianping Li, Lei Ye, Kang Zhou, Yuan Li, Yang Yang, Guangxin Peng, Liping Jing and Fengkui Zhang
    Citation: Experimental Hematology & Oncology 2023 12:16
  23. Neutrophil extracellular traps (NETs) is the key means for neutrophils to resist bacterial invasion. Sepsis is a systemic inflammatory response syndrome caused by infection.

    Authors: Wenjin Guo, Qian Gong, Xiaofeng Zong, Dianjun Wu, Yuhang Li, Huijie Xiao, Jie Song, Sheng Zhang, Shoupeng Fu, Zhichun Feng and Lu Zhuang
    Citation: Experimental Hematology & Oncology 2023 12:15
  24. The past decade has witnessed ongoing progress in immune therapy to ameliorate human health. As an emerging technique, chimeric antigen receptor (CAR) T-cell therapy has the advantages of specific killing of c...

    Authors: Ting Yan, Lingfeng Zhu and Jin Chen
    Citation: Experimental Hematology & Oncology 2023 12:14
  25. CD8+ T cells play an essential role against tumors but the role of human CD8+CD26+ T cell subset against tumors, in particular, haematological cancers such as chronic lymphocytic leukemia (CLL) remains unknown. A...

    Authors: Najmeh Bozorgmehr, Mark Hnatiuk, Anthea C. Peters and Shokrollah Elahi
    Citation: Experimental Hematology & Oncology 2023 12:13
  26. Circular RNAs (circRNAs) are emerging as new players in leukemogenic mechanisms. In patients with T-cell Acute Lymphoblastic Leukemia (T-ALL), the recent report of a remarkable dysregulation of circRNAs incite...

    Authors: Alessia Buratin, Cristina Borin, Caterina Tretti Parenzan, Anna Dal Molin, Silvia Orsi, Andrea Binatti, Katharina Simon, Maddalena Paganin, Valentina Serafin, Enrico Gaffo, Geertruij te Kronnie, Pieter Van Vlierberghe, Silvia Bresolin and Stefania Bortoluzzi
    Citation: Experimental Hematology & Oncology 2023 12:12
  27. Adult hematopoietic stem cells (HSCs) homeostasis is critically important in maintaining lifelong hematopoiesis. However, how adult HSCs orchestrate its homeostasis remains not fully understood. Imprinted gene...

    Authors: Deyu Huang, Yingli Han, Tian Tang, Lin Yang, Penglei Jiang, Wenchang Qian, Zhaoru Zhang, Xinyue Qian, Xin Zeng and Pengxu Qian
    Citation: Experimental Hematology & Oncology 2023 12:11
  28. Immunotherapy has become the central pillar of cancer therapy. Immune checkpoint inhibitors (ICIs), a major category of tumor immunotherapy, reactivate preexisting anticancer immunity. Initially, ICIs were app...

    Authors: Weijie Ma, Ruobing Xue, Zheng Zhu, Hizra Farrukh, Wenru Song, Tianhong Li, Lei Zheng and Chong-xian Pan
    Citation: Experimental Hematology & Oncology 2023 12:10
  29. Hepatocellular carcinoma (HCC) is one of the most lethal malignant tumors. Cell division cycle associated 8 (CDCA8) is an important multifactorial regulator in cancers. However, its up and downstream targets a...

    Authors: Erbao Chen, Yu He, Jing Jiang, Jing Yi, Zhilin Zou, Qiuzi Song, Qingqi Ren, Zewei Lin, Yi Lu, Jikui Liu and Jian Zhang
    Citation: Experimental Hematology & Oncology 2023 12:9
  30. In this study, we established a novel immunologic gene prognostic index (IGPI) to predict metastasis and provided new insights into tumor immune microenvironment (TIME) for PCa patients receiving radical radio...

    Authors: Dechao Feng, Weizhen Zhu, Xu Shi, Zhihong Wang, Wuran Wei, Qiang Wei, Lu Yang and Ping Han
    Citation: Experimental Hematology & Oncology 2023 12:8
  31. Caspase-8 (Casp8) acts as an initiator in cell apoptosis signaling. However, the role of Casp8 in tuning the tumor immune microenvironment remains controversial due to the complicated crosstalk between immune-...

    Authors: Zhihua Gong, Qingzhu Jia, Jinming Guo, Chongyi Li, Shouxia Xu, Zheng Jin, Han Chu, Yisong Y. Wan, Bo Zhu and Yi Zhou
    Citation: Experimental Hematology & Oncology 2023 12:7
  32. Cytidine triphosphate synthase 2 (CTPS2) is an essential metabolic enzyme that catalyzes the biosynthesis of CTP. CTP synthases contribute to lymphocytes proliferation and tumorigenesis, but the role of CTPS2 ...

    Authors: Xinting Hu, Yang Han, Jiarui Liu, Hua Wang, Zheng Tian, Xin Zhang, Ya Zhang and Xin Wang
    Citation: Experimental Hematology & Oncology 2023 12:6
  33. T-cell acute lymphoblastic leukemia (T-ALL) is a challenging pediatric and adult haematologic disease still associated with an unsatisfactory cure rate. Unlike B-ALL, the availability of novel therapeutic opti...

    Authors: Daniele Caracciolo, Antonia Mancuso, Nicoletta Polerà, Caterina Froio, Giuseppe D’Aquino, Caterina Riillo, Pierosandro Tagliaferri and Pierfrancesco Tassone
    Citation: Experimental Hematology & Oncology 2023 12:5
  34. αB-Crystallin is a heat shock chaperone protein which binds to misfolded proteins to prevent their aggregation. It is overexpressed in a wide-variety of cancers. Previous studies using human cancer cell lines ...

    Authors: Behnam Rashidieh, Amanda Louise Bain, Simon Manuel Tria, Sowmya Sharma, Cameron Allan Stewart, Jacinta Ley Simmons, Pirjo M. Apaja, Pascal H. G. Duijf, John Finnie and Kum Kum Khanna
    Citation: Experimental Hematology & Oncology 2023 12:4
  35. Breast cancer heterogeneity determines cancer progression, treatment effects, and prognosis. However, the precise mechanism for this heterogeneity remains unknown owing to its complexity. Here, we summarize th...

    Authors: Liantao Guo, Deguang Kong, Jianhua Liu, Ling Zhan, Lan Luo, Weijie Zheng, Qingyuan Zheng, Chuang Chen and Shengrong Sun
    Citation: Experimental Hematology & Oncology 2023 12:3

    The Correction to this article has been published in Experimental Hematology & Oncology 2024 13:7

  36. Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal inflammatory clinical condition, in which an exaggerated immune response is ineffectively regulated. Although etoposide-containing regimens are g...

    Authors: Timo C. E. Zondag, Aglina Lika and Jan A. M. van Laar
    Citation: Experimental Hematology & Oncology 2023 12:2
  37. N6-methyladenosine (m6A) is a prevalent modification of mRNA and is known to play important roles in tumorigenesis in many types of cancer. The function of N6-methyladenosine (m6A) RNA methylation depends on a...

    Authors: Weijian Wang, Qibo Huang, Zhibin Liao, Hongwei Zhang, Yachong Liu, Furong Liu, Xiaoping Chen, Bixiang Zhang, Yan Chen and Peng Zhu
    Citation: Experimental Hematology & Oncology 2023 12:1
  38. The treatment landscape of classical Hodgkin lymphoma (cHL) has undergone significant changes over the past 20 years. Gradual improvements have been made in the management of cHL patients, particularly in prol...

    Authors: Walter Hanel, Alex F. Herrera and Narendranath Epperla
    Citation: Experimental Hematology & Oncology 2022 11:108
  39. Breast cancer is the most common malignancy and the second leading cause of cancer-related death in women. Recent studies have indicated that aberrant activation of Rho GTPases relates to the malignant propert...

    Authors: Ming Yi, Di Zhang, Bin Song, Bin Zhao, Mengke Niu, Yuze Wu, Zhijun Dai and Kongming Wu
    Citation: Experimental Hematology & Oncology 2022 11:107
  40. Brain metastasis accounts for a large number of cancer-related deaths. The host immune system, involved at each step of the metastatic cascade, plays an important role in both the initiation of the brain metas...

    Authors: Wei-Wei Chen, Timothy Shun Man Chu, LiangLiang Xu, Cai-Ning Zhao, Wai-Sang Poon, Gilberto Ka-Kit Leung and Feng-Ming (Spring) Kong
    Citation: Experimental Hematology & Oncology 2022 11:105
  41. Breast cancer is one the most common cause of cancer death in women worldwide. We report here the first phase II study investigating a virus genetically engineered for tumor-selective replication in patients w...

    Authors: Sophie Cousin, Maud Toulmonde, Michèle Kind, Jean-Philippe Guegan, Alban Bessede, Coralie Cantarel, Carine Bellera and Antoine Italiano
    Citation: Experimental Hematology & Oncology 2022 11:104
  42. Acute promyelocytic leukemia (APL) is highly aggressive and is frequently associated with disseminated intravascular coagulation and high early death rates. Although all-trans retinoic acid (RA) induces comple...

    Authors: Xubo Gong, Piaoping Kong, Teng Yu, Xibin Xiao, Lin Wang, Yiwen Sang, Xiang Li, Bin Zhang, Zhihua Tao and Weiwei Liu
    Citation: Experimental Hematology & Oncology 2022 11:103
  43. Unlike many solid tumors, epithelial ovarian cancer (EOC) has a clear metastatic predilection to the adipocyte-rich niche, especially the omentum. However, the underlying mechanism driving this process remains...

    Authors: Chen Wang, Taiyang Ye, Wenjing Wang, Keqi Song, Jie Zhu, Lan Dai and Wen Di
    Citation: Experimental Hematology & Oncology 2022 11:102
  44. Programmed cell death protein 1(PD-1) is a type of immune-inhibitory checkpoint protein, which delivers inhibitory signals to cytotoxic T cells by binding to the programmed death ligand-1 (PD-L1) displayed on ...

    Authors: Mengyuan Dai, Miao Liu, Hua Yang, Can Küçük and Hua You
    Citation: Experimental Hematology & Oncology 2022 11:101

    The Publisher Correction to this article has been published in Experimental Hematology & Oncology 2022 11:106

  45. Neutrophil extracellular traps (NETs) released by activated neutrophils typically consist of DNA-histone complexes and granule proteins. NETs were originally identified as a host defense system against foreign...

    Authors: Yue Chen, Haoyue Hu, Songtao Tan, Qionglan Dong, Xue Fan, Yi Wang, Huan Zhang and Jun He
    Citation: Experimental Hematology & Oncology 2022 11:99
  46. Uterine and ovarian cancers are the most common gynecologic cancers. N6−methyladenosine (m6A), an important internal RNA modification in higher eukaryotes, has recently become a hot topic in epigenetic studies. N...

    Authors: Jiahua Chen, Bao Guo, Xiaojing Liu, Jing Zhang, Junhui Zhang, Yuan Fang, Suding Zhu, Bing Wei, Yunxia Cao and Lei Zhan
    Citation: Experimental Hematology & Oncology 2022 11:98

Annual Journal Metrics

  • 2022 Citation Impact
    11.4 - 2-year Impact Factor
    7.3 - 5-year Impact Factor
    1.609 - SNIP (Source Normalized Impact per Paper)
    1.908 - SJR (SCImago Journal Rank)

    2023 Speed
    4 days submission to first editorial decision for all manuscripts (Median)
    100 days submission to accept (Median)

    2023 Usage
    696,150 downloads
    375 Altmetric mentions