Fig. 5

Luminal cell trajectory analysis. (A–C). Monocle 2 trajectory plot showing luminal subcluster and state dynamics; (D). Three representative genes with different expression patterns in the process of luminal cell differentiation: MAZ, POTEN, and SPN; (E). Hierarchical clustering heatmap showing four subclusters of differentially expressed genes along with luminal cell pseudotime. (F). Hierarchical clustering heatmap showing four subclusters of differentially expressed genes along with pseudotime for three cell types (from cell fate1 to cell fate2)