Fig. 1

Fourteen cell types in PCa were identified by scRNA-seq. (A). Study flow chart; (B). Main cell clusters in PCa tissue demonstrated using uniform manifold approximation and projection (UMAP) analysis are colored and labeled according to their featured gene expression profiles. (C). Cell numbers and percentages of each cluster in each sample; (D). Marker gene expression for each cell type, where dot size and color represent percentage of marker gene expression (pct. exp) and averaged scaled expression (avg. exp. scale) value, respectively; (E). Heatmap generated based on expression levels of top ten marker genes in each cluster