Skip to main content

Table 2 Subgroup analysis of local control rate

From: Comparison of local ablative therapies, including radiofrequency ablation, microwave ablation, stereotactic ablative radiotherapy, and particle radiotherapy, for inoperable hepatocellular carcinoma: a systematic review and meta-analysis

Groups

Cohorts (n)

Patients (n)

Events (95%)

I 2

Relative risk (95%)

p

Local control rate

      

 50 mm

      

  SABR

1

102

0.716 (0.621–0.795)

0.000

1

  Particle

1

24

0.875 (0.676–0.959)

0.000

0.818 (0.674–0.994)

0.043

 < 50 mm

      

  RFA

7

651

0.822 (0.730–0.888)

16.549

1

  MWA

5

569

0.926 (0.866–0.960)

0.000

0.888 (0.851–0.926)

< 0.001

  SABR

6

322

0.872 (0.787–0.927)

32.839

0.943 (0.892–0.996)

0.035

  Particle

2

94

0.909 (0.766–0.968)

0.000

0.904 (0.840–0.973)

0.007

 30 mm

      

  RFA

3

404

0.724 (0.524–0.862)

7.164

1

  SABR

5

347

0.821 (0.698–0.901)

25.909

0.882 (0.816–0.953)

0.002

  Particle

3

118

0.899 (0.766–0.961)

0.000

0.805 (0.739–0.877)

< 0.001

 < 30 mm

      

    RFA

4

247

0.888 (0.841–0.922)

0.000

1

  MWA

4

510

0.907 (0.878–0.930)

32.375

0.979 (0.929–1.032)

0.427

  SABR

2

77

0.932 (0.846–0.971)

0.000

0.953 (0.884–1.027)

0.205

 20 mm

      

  RFA

5

468

0.773 (0.636–0.869)

0.000

1

  MWA

3

412

0.914 (0.819–0.962)

0.000

0.846 (0.799–0.896)

< 0.001

  SABR

7

424

0.851 (0.763–0.910)

0.000

0.908 (0.853–0.968)

0.003

  Particle

3

118

0.899 (0.775–0.959)

31.931

0.860 (0.795–0.930)

< 0.001

 < 20 mm

      

  RFA

2

183

0.900 (0.847–0.936)

0.000

1

  MWA

1

98

0.939 (0.870–0.972)

0.000

0.958 (0.894–1.028)

0.234

  1. MWA: Microwave ablation; RFA: radiofrequency ablation; SABR: stereotactic ablative radiotherapy