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Table 1 Patient and treatment characteristics

From: PD-L1+ macrophages are associated with favorable features in primary mediastinal (thymic) large B-cell lymphoma

Deidentified number

Gender

Race

Ethnicity

Age at diagnosis

B-SX at DX

Initial stage

IPI

Bulky  > 10 cm

1st line of therapy

At least one relapse

2nd line of therapy

3rd line of therapy

4th line of therapy

FU in

months

Status at last FU

PML01

Male

white

not Hispanic

46

No

II

1

Yes

6xDA-R-EPOCH

No

   

18

Alive

PML02

Female

Asian

not Hispanic

30

No

II

1

Yes

6xDA-R-EPOCH

No

   

32

Alive

PML03

Male

white

Hispanic

36

No

IV

2

No

6xDA-R-EPOCH

No

   

21

Alive

PML04

Male

white

not Hispanic

54

No

IV

2

Yes

6xDA-R-EPOCH

Yes

3xR-ICE, ASCT and XRT

  

65

Alive

PML05

Male

American Indian

not Hispanic

38

No

I

1

Yes

6xDA-R-EPOCH

No

   

26

Alive

PML06

Female

Hawaiian/Pacific Islander

Hispanic

29

Yes

II

1

Yes

6xDA-R-EPOCH

Yes

1 × R-DHAP

1xR-ICE, Liso-cel

 

29

Alive

PML07

Male

white

NA

30

Yes

III

1

Yes

1xABVD + 6xDA-R-EPOCH

Yes

3xR-DHAP, then ASCT

Selinexor and Rituximab

Rituximab + fractionated Cyclophosphamide

15

Dead

PML08

Female

white

not Hispanic

24

Yes

IV

2

No

6xDA-R-EPOCH

No

   

38

Alive

PML09

Female

white

not Hispanic

50

Yes

IV

3

Yes

6xDA-R-EPOCH

Yes

1xR-DHAP

Tisa-cel

7xPembrolizumab + XRT

31

Alive

PML10

Male

white

not Hispanic

22

No

II

0

No

4xDA-R-EPOCH

No

   

35

Alive

PML11

Male

white

not Hispanic

38

Yes

III

1

No

1xR-CHOP + Len,

 + 5xDA-R-EPOCH

No

   

37

Alive

PML12

Female

white

not Hispanic

28

No

IV

1

No

5xDA-R-EPOCH

Yes

Axi-cel

8xPembrolizumab, ASCT and XRT

 

57

Alive

  1. ABVD: doxorubicin hydrochloride, bleomycin sulfate, vinblastine sulfate, and dacarbazine; ASCT: autologous stem cell transplantation; axi-cel: axicabtagene ciloleucel; DA-R-EPOCH: dose-adjusted rituximab, etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin; DX: diagnosis; FU: follow-up; IPI: International Prognostic Index; Len: lenalidomide; Liso-cel: lisocabtagene maraleucel; NA: not available; R-DHAP: rituximab, cytosine arabinoside, dexamethasone; R-ICE: rituximab, ifosfamide, carboplatin, and etoposide; SX: symptoms;Tisa-cel: tisagenlecleucel; x: cycles; XRT: radiotherapy of the mediastinum