Fig. 1

ASAP2 is upregulated in hepatocellular carcinoma (HCC). A Heatmap for expression patterns of ASAP1, ASAP2, and ASAP3 in the indicated gene expression omnibus (GEO) datasets; “*” indicates 0.01 < P < 0.05, “**” indicates 0.001 < P < 0.01, “***” indicates P < 0.001. B Comparison of ASAP2 expression levels between normal liver and HCC tissues in The Cancer Genome Atlas (TCGA) dataset according to the Starbase 3.0 dataset. C Comparison of ASAP2 expression levels between paired normal liver and HCC tissues in TCGA dataset. D ASAP2 expression levels in HCC patients with different clinical stages in TCGA dataset according to the Gene Expression Profiling Interactive Analysis (GEPIA) dataset. E qRT-PCR results of ASAP2 mRNA expression levels between paired normal liver and HCC tissues collected from Fudan University Shanghai Cancer Center (FUSCC). F Western blot results of ASAP2 protein expression levels between paired normal liver and HCC tissues collected from FUSCC. G Representative immunohistochemistry staining images for ASAP2 in normal liver and HCC tissues collected from FUSCC. H Distribution of ASAP2 expression states in normal liver and HCC tissues collected from FUSCC. I Correlation between DNA copy number and mRNA expression levels of ASAP2 in HCC in TCGA dataset according to the cbioportal dataset. J Association between mRNA expression levels and DNA methylation pattern of ASAP2 in HCC according to TCGA dataset