Table 2 Genetic abnormality of AML patients respect to RCC1 expression
Genetic abnormality | total (n = 77) | low RCC1 expression (n = 57) | high RCC1 expression (n = 20) | p-value | |||
|---|---|---|---|---|---|---|---|
| Â | n | % | n | % | n | % | Â |
RUNX1 | 7 | 9.1 | 5 | 8.8 | 2 | 10.0 | 1.00 |
TP53 | 7 | 9.1 | 3 | 5.3 | 4 | 20.0 | 0.07 |
ASXL1 | 11 | 14.3 | 7 | 12.3 | 4 | 20.0 | 0.46 |
GATA2 | 5 | 6.5 | 3 | 5.3 | 2 | 10.0 | 0.60 |
NPM1 | 11 | 14.3 | 10 | 17.5 | 1 | 5.0 | 0.27 |
CEBPA | 6 | 7.8 | 5 | 8.8 | 1 | 5.0 | 1.00 |
FLT3 | 11 | 14.3 | 9 | 15.8 | 2 | 10.0 | 0.72 |
KMT2A rearrangement | 6 | 7.8 | 2 | 3.5 | 4 | 20.0 | 0.04 |
t(8;21)/AML-ETO | 7 | 9.1 | 6 | 10.5 | 1 | 5.0 | 0.67 |
CBFB-MYH11 | 6 | 7.8 | 6 | 10.5 | 0 | 0.0 | 0.33 |
DEK-NUP214 | 2 | 2.6 | 2 | 3.5 | 0 | 0.0 | 1.00 |
BCR-ABL1 | 1 | 1.3 | 1 | 1.8 | 0 | 0.0 | 1.00 |
−7/7q | 8 | 10.4 | 5 | 8.8 | 3 | 15.0 | 0.42 |
 + 8 | 6 | 7.8 | 4 | 7.0 | 2 | 10.0 | 0.65 |
−5/5q | 6 | 7.8 | 3 | 5.3 | 3 | 15.0 | 0.18 |
−17/17p | 5 | 6.5 | 3 | 5.3 | 2 | 10.0 | 0.60 |
Normal karyotype | 41 | 56.9 | 34 | 60.7 | 7 | 43.8 | 0.262 |
Complex karyotype | 9 | 12.5 | 3 | 5.4 | 6 | 37.5 | 0.003 |