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Fig. 8 | Experimental Hematology & Oncology

Fig. 8

From: Synergistic effect of HDAC inhibitor Chidamide with Cladribine on cell cycle arrest and apoptosis by targeting HDAC2/c-Myc/RCC1 axis in acute myeloid leukemia

Fig. 8

The elevated expression levels of RCC1 in AML patients’ bone marrow samples in our clinical center analyzed by RT-qPCR. (A) The elevated expression levels of RCC1 in AML versus normal donors. (B) The elevated expression levels of RCC1 in AML patients from the Adverse group and Intermediate group compare to the Favorable one. (C) The elevated expression levels of RCC1 in AML patients with complex karyotypes. The overall survival curves of RCC1high or RCC1low groups in AML patients cohort (D) and de novo cohort (E). The relapse-free survival curves of RCC1highor RCC1low groups in AML patients cohort (F). *p < 0.05, **p < 0.01, ***p < 0.001

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