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Fig. 3 | Experimental Hematology & Oncology

Fig. 3

From: Synergistic effect of HDAC inhibitor Chidamide with Cladribine on cell cycle arrest and apoptosis by targeting HDAC2/c-Myc/RCC1 axis in acute myeloid leukemia

Fig. 3

The synergistic cell cycle effect of Chidamide (CHI) and Cladribine (CLA) in AML cells. The flow cytometry histogram (A) and statistic histogram (B) of cell cycle effect in U937 cells and THP-1 cells that were treated by CHI alone, CLA alone, and two drugs combination for 48 h. (C) Western blot of cyclin E2, CDK2, and p21 Waf1/Cip1 in U937 cells and THP-1 cells that were treated with CHI alone, CLA alone, and two drugs combination for 48 h. *p < 0.05, **p < 0.01, ***p < 0.001

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Experimental Hematology & Oncology

ISSN: 2162-3619

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