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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: Synergistic effect of HDAC inhibitor Chidamide with Cladribine on cell cycle arrest and apoptosis by targeting HDAC2/c-Myc/RCC1 axis in acute myeloid leukemia

Fig. 2

The synergistic effect of Chidamide (CHI) and Cladribine (CLA) in AML cells. The cell proliferation assays in (A) U937 cells and (B) THP-1 cells were treated by CHI alone with gradient concentration or CHI combined with 0.01, 0.02 or 0.04 μM CLA for 48 h. The normalized isobologram plot of the combination of CHI and CLA in (C) U937 cells and (D) THP-1 cells. *p < 0.05, **p < 0.01, ***p < 0.001

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Experimental Hematology & Oncology

ISSN: 2162-3619

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