Fig. 1

The inhibition effects of Chidamide (CHI) alone in AML cells. The cell proliferation assays in (A) U937 cells and (B) THP-1 cells were treated by CHI alone with gradient concentration for 24, 48, and 72 h. The statistic histogram and flow cytometry histogram of cell cycle effect in (C, E) U937 cells and (D, F) THP-1 cells that were treated by CHI alone with gradient concentration for 48 h. The statistic histogram and flow cytometry scatter plot of apoptosis effect in (G, I) U937 cells and (H, J) THP-1 cells that were treated by CHI alone with gradient concentration for 48 h. *p < 0.05, **p < 0.01, ***p < 0.001