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Fig. 2 | Experimental Hematology & Oncology

Fig. 2

From: p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma

Fig. 2

CDC20 mRNA expression was associated with the therapeutic effect and prognosis of MCL patients. Among 24 MCL patients with PBMCs extracted, CDC20 mRNA expression was significantly different in the subgroups of treatment response (A), MIPI score (B), and MIPI-c score (C). A Patients were divided into the CR/PR group and the PD/SD group according to treatment response, and CDC20 mRNA expression level between the two groups was compared. B Patients were divided into the low risk group, the intermediate risk group and the high risk group according to MIPI score, and CDC20 mRNA expression level among the three groups was compared. C Patients were divided into the low risk group, low-intermediate risk group, high-intermediate risk group, and the high risk group according to MIPI-c score, and CDC20 mRNA expression level among the four groups was compared. D The relationship between CDC20 expression level and overall survival of MCL patients was analyzed via GSE93291 dataset (n = 123). *P < 0.05, **P < 0.01, ***P < 0.001, ns meant P > 0.05

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